A new method for the generation of azoalkenes from ketohydrazones and its application to the synthesis of tetrahydropyridazine derivatives

S. L. Gaonkar, K. M. Lokanatha Rai

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

The reaction of ketohydrazones containing an α-methylene group with chloramine-T followed by treatment with triethylamine leads to the formation of azoalkenes via an α-chloroazo-compound, which can react intermolecularly and in situ with olefinic compounds to produce tetrahydropyridazine derivatives in good yield.

Original languageEnglish
Pages (from-to)5969-5970
Number of pages2
JournalTetrahedron Letters
Volume46
Issue number35
DOIs
Publication statusPublished - 29-08-2005

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Derivatives
triethylamine
chloramine-T

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

Cite this

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A new method for the generation of azoalkenes from ketohydrazones and its application to the synthesis of tetrahydropyridazine derivatives. / Gaonkar, S. L.; Lokanatha Rai, K. M.

In: Tetrahedron Letters, Vol. 46, No. 35, 29.08.2005, p. 5969-5970.

Research output: Contribution to journalArticle

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AU - Gaonkar, S. L.

AU - Lokanatha Rai, K. M.

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AB - The reaction of ketohydrazones containing an α-methylene group with chloramine-T followed by treatment with triethylamine leads to the formation of azoalkenes via an α-chloroazo-compound, which can react intermolecularly and in situ with olefinic compounds to produce tetrahydropyridazine derivatives in good yield.

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