A new method for the generation of azoalkenes from ketohydrazones and its application to the synthesis of tetrahydropyridazine derivatives

S. L. Gaonkar, K. M. Lokanatha Rai

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Abstract

The reaction of ketohydrazones containing an α-methylene group with chloramine-T followed by treatment with triethylamine leads to the formation of azoalkenes via an α-chloroazo-compound, which can react intermolecularly and in situ with olefinic compounds to produce tetrahydropyridazine derivatives in good yield.

Original languageEnglish
Pages (from-to)5969-5970
Number of pages2
JournalTetrahedron Letters
Volume46
Issue number35
DOIs
Publication statusPublished - 29-08-2005

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All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

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