A new method for the generation of azoalkenes from ketohydrazones and its application to the synthesis of tetrahydropyridazine derivatives

S. L. Gaonkar; K. M. Lokanatha Rai

doi:10.1016/j.tetlet.2005.06.007

A new method for the generation of azoalkenes from ketohydrazones and its application to the synthesis of tetrahydropyridazine derivatives

S. L. Gaonkar, K. M. Lokanatha Rai

Department of Chemistry, Manipal Institute of Technology, Manipal

Research output: Contribution to journal › Article › peer-review

20 Citations (Scopus)

Abstract

The reaction of ketohydrazones containing an α-methylene group with chloramine-T followed by treatment with triethylamine leads to the formation of azoalkenes via an α-chloroazo-compound, which can react intermolecularly and in situ with olefinic compounds to produce tetrahydropyridazine derivatives in good yield.

Original language	English
Pages (from-to)	5969-5970
Number of pages	2
Journal	Tetrahedron Letters
Volume	46
Issue number	35
DOIs	https://doi.org/10.1016/j.tetlet.2005.06.007
Publication status	Published - 29-08-2005

All Science Journal Classification (ASJC) codes

Biochemistry
Organic Chemistry
Drug Discovery

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10.1016/j.tetlet.2005.06.007

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abstract = "The reaction of ketohydrazones containing an α-methylene group with chloramine-T followed by treatment with triethylamine leads to the formation of azoalkenes via an α-chloroazo-compound, which can react intermolecularly and in situ with olefinic compounds to produce tetrahydropyridazine derivatives in good yield.",

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Y1 - 2005/8/29

N2 - The reaction of ketohydrazones containing an α-methylene group with chloramine-T followed by treatment with triethylamine leads to the formation of azoalkenes via an α-chloroazo-compound, which can react intermolecularly and in situ with olefinic compounds to produce tetrahydropyridazine derivatives in good yield.

AB - The reaction of ketohydrazones containing an α-methylene group with chloramine-T followed by treatment with triethylamine leads to the formation of azoalkenes via an α-chloroazo-compound, which can react intermolecularly and in situ with olefinic compounds to produce tetrahydropyridazine derivatives in good yield.

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A new method for the generation of azoalkenes from ketohydrazones and its application to the synthesis of tetrahydropyridazine derivatives

Abstract

All Science Journal Classification (ASJC) codes

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