A new role for vitamin D: Cholecalciferol promotes dermal wound strength and re-epithelization

K. V. Ramesh, M. B. Mahindrakar, E. P. Bhat

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Vitamin D endocrine system is a potent regulator of cell growth and maturation. Vitamin D3 modulates growth kinetics of many cells and produces divergent actions. Keeping this in view, cholecalciferol is evaluated for its actions on dermal wound healing in Wistar rats. Intraperitonial cholecalciferol at 5, 10, 15 IU/g body weight doses produces increases in wound breaking strength and promotes epithelization significantly. Results suggest that there is some biological role for vitamin D endocrine system, in wound repair. A clear understanding of this role of vitamin D3 may define new avenues in wound medication.

Original languageEnglish
Pages (from-to)778-779
Number of pages2
JournalIndian Journal of Experimental Biology
Volume31
Issue number9
Publication statusPublished - 01-12-1993
Externally publishedYes

Fingerprint

Cholecalciferol
Vitamins
Vitamin D
Skin
Endocrine System
Wounds and Injuries
Growth kinetics
Cell growth
Growth
Wound Healing
Wistar Rats
Rats
Repair
Cells
Body Weight

All Science Journal Classification (ASJC) codes

  • Bioengineering

Cite this

Ramesh, K. V. ; Mahindrakar, M. B. ; Bhat, E. P. / A new role for vitamin D : Cholecalciferol promotes dermal wound strength and re-epithelization. In: Indian Journal of Experimental Biology. 1993 ; Vol. 31, No. 9. pp. 778-779.
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A new role for vitamin D : Cholecalciferol promotes dermal wound strength and re-epithelization. / Ramesh, K. V.; Mahindrakar, M. B.; Bhat, E. P.

In: Indian Journal of Experimental Biology, Vol. 31, No. 9, 01.12.1993, p. 778-779.

Research output: Contribution to journalArticle

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