TY - JOUR
T1 - A new role for vitamin D
T2 - Cholecalciferol promotes dermal wound strength and re-epithelization
AU - Ramesh, K. V.
AU - Mahindrakar, M. B.
AU - Bhat, E. P.
PY - 1993/12/1
Y1 - 1993/12/1
N2 - Vitamin D endocrine system is a potent regulator of cell growth and maturation. Vitamin D3 modulates growth kinetics of many cells and produces divergent actions. Keeping this in view, cholecalciferol is evaluated for its actions on dermal wound healing in Wistar rats. Intraperitonial cholecalciferol at 5, 10, 15 IU/g body weight doses produces increases in wound breaking strength and promotes epithelization significantly. Results suggest that there is some biological role for vitamin D endocrine system, in wound repair. A clear understanding of this role of vitamin D3 may define new avenues in wound medication.
AB - Vitamin D endocrine system is a potent regulator of cell growth and maturation. Vitamin D3 modulates growth kinetics of many cells and produces divergent actions. Keeping this in view, cholecalciferol is evaluated for its actions on dermal wound healing in Wistar rats. Intraperitonial cholecalciferol at 5, 10, 15 IU/g body weight doses produces increases in wound breaking strength and promotes epithelization significantly. Results suggest that there is some biological role for vitamin D endocrine system, in wound repair. A clear understanding of this role of vitamin D3 may define new avenues in wound medication.
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M3 - Article
C2 - 8276449
AN - SCOPUS:0027891845
SN - 0019-5189
VL - 31
SP - 778
EP - 779
JO - Journal of scientific & industrial research. C. Biological sciences
JF - Journal of scientific & industrial research. C. Biological sciences
IS - 9
ER -