A novel subtype of myeloproliferative disorder? JAK2V617F-associated hypereosinophilia with hepatic venous thrombosis

Sowjanya Dasari, Kushal Naha, Manjunath Hande, G. Vivek

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We report the case of a 27-year-old man, presenting with one episode of massive haematemesis and a history of persistent eosinophilia for the past 8 months. An evaluation revealed hepatic cirrhosis with portal hypertension, secondary to chronic Budd-Chiari syndrome. Further investigations confirmed a diagnosis of hypereosinophilic syndrome. Molecular genetic analysis was negative for FIP1L1-PDGFRA gene rearrangement, but positive for JAK2V617F mutation.

Original languageEnglish
Article number200087
JournalBMJ Case Reports
Publication statusPublished - 30-08-2013


All Science Journal Classification (ASJC) codes

  • Medicine(all)

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