A pilot study to evaluate urine LAM assay for diagnosis of pulmonary tuberculosis among non-HIV patients

Akshita Gupta; Ajay Kumar; Asem Ali Ashraf; Haritha Madigubba; Kiran Chawla

doi:10.1177/0049475520936164

A pilot study to evaluate urine LAM assay for diagnosis of pulmonary tuberculosis among non-HIV patients

Akshita Gupta, Ajay Kumar, Asem Ali Ashraf, Haritha Madigubba, Kiran Chawla

Research output: Contribution to journal › Article › peer-review

Abstract

There is a great need to improve diagnostic tools for tuberculosis where the majority are without HIV co-infection in resource-poor settings and high-burden areas such as India. The urine LAM assay has not hitherto been studied and may have a role to play. Our study found that, as a stand-alone diagnostic tool, the assay was suboptimal when compared to Xpert MTB/Rif. However, a combination of LAM assay along with sputum microscopy may be useful in settings where molecular testing is unavailable.

Original language	English
Journal	Tropical Doctor
DOIs	https://doi.org/10.1177/0049475520936164
Publication status	Published - 01-10-2020

All Science Journal Classification (ASJC) codes

Public Health, Environmental and Occupational Health
Infectious Diseases

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1177/0049475520936164

Cite this

@article{b2722e3a92ee471388bea9f3e7463507,

title = "A pilot study to evaluate urine LAM assay for diagnosis of pulmonary tuberculosis among non-HIV patients",

abstract = "There is a great need to improve diagnostic tools for tuberculosis where the majority are without HIV co-infection in resource-poor settings and high-burden areas such as India. The urine LAM assay has not hitherto been studied and may have a role to play. Our study found that, as a stand-alone diagnostic tool, the assay was suboptimal when compared to Xpert MTB/Rif. However, a combination of LAM assay along with sputum microscopy may be useful in settings where molecular testing is unavailable.",

author = "Akshita Gupta and Ajay Kumar and Ashraf, {Asem Ali} and Haritha Madigubba and Kiran Chawla",

year = "2020",

month = oct,

day = "1",

doi = "10.1177/0049475520936164",

language = "English",

journal = "Tropical Doctor",

issn = "0049-4755",

publisher = "SAGE Publications Ltd",

}

TY - JOUR

T1 - A pilot study to evaluate urine LAM assay for diagnosis of pulmonary tuberculosis among non-HIV patients

AU - Gupta, Akshita

AU - Kumar, Ajay

AU - Ashraf, Asem Ali

AU - Madigubba, Haritha

AU - Chawla, Kiran

PY - 2020/10/1

Y1 - 2020/10/1

N2 - There is a great need to improve diagnostic tools for tuberculosis where the majority are without HIV co-infection in resource-poor settings and high-burden areas such as India. The urine LAM assay has not hitherto been studied and may have a role to play. Our study found that, as a stand-alone diagnostic tool, the assay was suboptimal when compared to Xpert MTB/Rif. However, a combination of LAM assay along with sputum microscopy may be useful in settings where molecular testing is unavailable.

AB - There is a great need to improve diagnostic tools for tuberculosis where the majority are without HIV co-infection in resource-poor settings and high-burden areas such as India. The urine LAM assay has not hitherto been studied and may have a role to play. Our study found that, as a stand-alone diagnostic tool, the assay was suboptimal when compared to Xpert MTB/Rif. However, a combination of LAM assay along with sputum microscopy may be useful in settings where molecular testing is unavailable.

UR - http://www.scopus.com/inward/record.url?scp=85087713917&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85087713917&partnerID=8YFLogxK

U2 - 10.1177/0049475520936164

DO - 10.1177/0049475520936164

M3 - Article

C2 - 32638652

AN - SCOPUS:85087713917

SN - 0049-4755

JO - Tropical Doctor

JF - Tropical Doctor

ER -

A pilot study to evaluate urine LAM assay for diagnosis of pulmonary tuberculosis among non-HIV patients

Abstract

All Science Journal Classification (ASJC) codes

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this