A rare case of haemolytic anaemia: Paroxysmal nocturnal haemoglobinuria

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Abstract

Paroxysmal Nocturnal Haemoglobinuria (PNH) is a rare disease. It is an acquired chronic haemolytic anaemia. It manifests as a triad of recurrent episodes of haemolysis, thrombotic episodes and pancytopaenia. A 32-year old gentleman presented with a history of gradually progressive generalized weakness. His clinical findings and laboratory investigations were suggestive of haemolytic anaemia and flow cytometry clinched the diagnosis of PNH.

Original languageEnglish
Pages (from-to)725-726
Number of pages2
JournalJournal of Clinical and Diagnostic Research
Volume6
Issue number4 SUPPL. 2
Publication statusPublished - 31-05-2012

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Paroxysmal Hemoglobinuria
Flow cytometry
Hemolytic Anemia
Rare Diseases
Hemolysis
Flow Cytometry

All Science Journal Classification (ASJC) codes

  • Medicine(all)
  • Clinical Biochemistry

Cite this

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title = "A rare case of haemolytic anaemia: Paroxysmal nocturnal haemoglobinuria",
abstract = "Paroxysmal Nocturnal Haemoglobinuria (PNH) is a rare disease. It is an acquired chronic haemolytic anaemia. It manifests as a triad of recurrent episodes of haemolysis, thrombotic episodes and pancytopaenia. A 32-year old gentleman presented with a history of gradually progressive generalized weakness. His clinical findings and laboratory investigations were suggestive of haemolytic anaemia and flow cytometry clinched the diagnosis of PNH.",
author = "Basavaprabhu Achappa and Deepak Madi and Satish Rao and Meghna Rao and Soundarya Mahalingam",
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AU - Achappa, Basavaprabhu

AU - Madi, Deepak

AU - Rao, Satish

AU - Rao, Meghna

AU - Mahalingam, Soundarya

PY - 2012/5/31

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N2 - Paroxysmal Nocturnal Haemoglobinuria (PNH) is a rare disease. It is an acquired chronic haemolytic anaemia. It manifests as a triad of recurrent episodes of haemolysis, thrombotic episodes and pancytopaenia. A 32-year old gentleman presented with a history of gradually progressive generalized weakness. His clinical findings and laboratory investigations were suggestive of haemolytic anaemia and flow cytometry clinched the diagnosis of PNH.

AB - Paroxysmal Nocturnal Haemoglobinuria (PNH) is a rare disease. It is an acquired chronic haemolytic anaemia. It manifests as a triad of recurrent episodes of haemolysis, thrombotic episodes and pancytopaenia. A 32-year old gentleman presented with a history of gradually progressive generalized weakness. His clinical findings and laboratory investigations were suggestive of haemolytic anaemia and flow cytometry clinched the diagnosis of PNH.

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