A rare case of haemolytic disease of newborn with Bombay phenotype mother

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

We are reporting a rare case of severe hemolytic disease of newborn (HDN) with Bombay phenotype mother. A retrospective study of a case with severe haemolytic disease of newborn with Bombay phenotype mother was done. Blood grouping, antibody screening, and lectin study was done on the blood sample of the baby and mother to confirm the diagnosis. Hematological and biochemical parameters were obtained from the hospital laboratory information system for the analysis. Blood group of the baby was A positive, direct antiglobulin test was negative. Blood group of the mother was confirmed to be Bombay phenotype, Hematological parameters showed all the signs of ongoing hemolysis and the bilirubin level was in the zone of exchange transfusion. Due to the unavailability of this rare phenotype blood unit, baby was managed conservatively. Anticipating the fetal anemia and HDN with mothers having Bombay phenotype and prior notification to the transfusion services will be of great help in optimizing the neonatal care and outcome.

Original languageEnglish
Pages (from-to)153-155
Number of pages3
JournalAsian Journal of Transfusion Science
Volume7
Issue number2
DOIs
Publication statusPublished - 01-07-2013

Fingerprint

Fetal Erythroblastosis
Phenotype
Blood Group Antigens
Clinical Laboratory Information Systems
Blood Grouping and Crossmatching
Hospital Information Systems
Coombs Test
Hospital Laboratories
Systems Analysis
Hemolysis
Bilirubin
Lectins
Anemia
Retrospective Studies
Antibodies

All Science Journal Classification (ASJC) codes

  • Immunology and Allergy
  • Hematology

Cite this

@article{d4732763600d4427b5477bcea5d05426,
title = "A rare case of haemolytic disease of newborn with Bombay phenotype mother",
abstract = "We are reporting a rare case of severe hemolytic disease of newborn (HDN) with Bombay phenotype mother. A retrospective study of a case with severe haemolytic disease of newborn with Bombay phenotype mother was done. Blood grouping, antibody screening, and lectin study was done on the blood sample of the baby and mother to confirm the diagnosis. Hematological and biochemical parameters were obtained from the hospital laboratory information system for the analysis. Blood group of the baby was A positive, direct antiglobulin test was negative. Blood group of the mother was confirmed to be Bombay phenotype, Hematological parameters showed all the signs of ongoing hemolysis and the bilirubin level was in the zone of exchange transfusion. Due to the unavailability of this rare phenotype blood unit, baby was managed conservatively. Anticipating the fetal anemia and HDN with mothers having Bombay phenotype and prior notification to the transfusion services will be of great help in optimizing the neonatal care and outcome.",
author = "Shamee Shastry and Lewis, {Leslie E.} and Bhat, {Sudha S.}",
year = "2013",
month = "7",
day = "1",
doi = "10.4103/0973-6247.115583",
language = "English",
volume = "7",
pages = "153--155",
journal = "Asian Journal of Transfusion Science",
issn = "0973-6247",
publisher = "Medknow Publications and Media Pvt. Ltd",
number = "2",

}

A rare case of haemolytic disease of newborn with Bombay phenotype mother. / Shastry, Shamee; Lewis, Leslie E.; Bhat, Sudha S.

In: Asian Journal of Transfusion Science, Vol. 7, No. 2, 01.07.2013, p. 153-155.

Research output: Contribution to journalArticle

TY - JOUR

T1 - A rare case of haemolytic disease of newborn with Bombay phenotype mother

AU - Shastry, Shamee

AU - Lewis, Leslie E.

AU - Bhat, Sudha S.

PY - 2013/7/1

Y1 - 2013/7/1

N2 - We are reporting a rare case of severe hemolytic disease of newborn (HDN) with Bombay phenotype mother. A retrospective study of a case with severe haemolytic disease of newborn with Bombay phenotype mother was done. Blood grouping, antibody screening, and lectin study was done on the blood sample of the baby and mother to confirm the diagnosis. Hematological and biochemical parameters were obtained from the hospital laboratory information system for the analysis. Blood group of the baby was A positive, direct antiglobulin test was negative. Blood group of the mother was confirmed to be Bombay phenotype, Hematological parameters showed all the signs of ongoing hemolysis and the bilirubin level was in the zone of exchange transfusion. Due to the unavailability of this rare phenotype blood unit, baby was managed conservatively. Anticipating the fetal anemia and HDN with mothers having Bombay phenotype and prior notification to the transfusion services will be of great help in optimizing the neonatal care and outcome.

AB - We are reporting a rare case of severe hemolytic disease of newborn (HDN) with Bombay phenotype mother. A retrospective study of a case with severe haemolytic disease of newborn with Bombay phenotype mother was done. Blood grouping, antibody screening, and lectin study was done on the blood sample of the baby and mother to confirm the diagnosis. Hematological and biochemical parameters were obtained from the hospital laboratory information system for the analysis. Blood group of the baby was A positive, direct antiglobulin test was negative. Blood group of the mother was confirmed to be Bombay phenotype, Hematological parameters showed all the signs of ongoing hemolysis and the bilirubin level was in the zone of exchange transfusion. Due to the unavailability of this rare phenotype blood unit, baby was managed conservatively. Anticipating the fetal anemia and HDN with mothers having Bombay phenotype and prior notification to the transfusion services will be of great help in optimizing the neonatal care and outcome.

UR - http://www.scopus.com/inward/record.url?scp=84882244826&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84882244826&partnerID=8YFLogxK

U2 - 10.4103/0973-6247.115583

DO - 10.4103/0973-6247.115583

M3 - Article

VL - 7

SP - 153

EP - 155

JO - Asian Journal of Transfusion Science

JF - Asian Journal of Transfusion Science

SN - 0973-6247

IS - 2

ER -