A rare case of recurrent pregnancy loss associated with high-titer positivity for perinuclear anti-neutrophilic cytoplasmic antibodies

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Abstract

We present a case of recurrent pregnancy loss associated with unusual constellation of utoimmunity-related features such as hypertension, severe hrombocytopenia, hypothyroidism and persistent high titers of perinuclear antineutrophilic cytoplasmic antibodies. Her clinical features did not fit into a particular diagnosis of vasculitides, systemic lupus erythematosis (SLE) or other known autoimmune diseases where this autoantibody is found in high titers. We report the unusual association of this autoantibody with recurrent early fetal demise in this case.

Original languageEnglish
Pages (from-to)221-222
Number of pages2
JournalJournal of Human Reproductive Sciences
Volume5
Issue number2
DOIs
Publication statusPublished - 01-05-2012

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Autoantibodies
Systemic Vasculitis
Pregnancy
Fetal Death
Antibodies
Hypothyroidism
Autoimmune Diseases
Hypertension

All Science Journal Classification (ASJC) codes

  • Reproductive Medicine

Cite this

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abstract = "We present a case of recurrent pregnancy loss associated with unusual constellation of utoimmunity-related features such as hypertension, severe hrombocytopenia, hypothyroidism and persistent high titers of perinuclear antineutrophilic cytoplasmic antibodies. Her clinical features did not fit into a particular diagnosis of vasculitides, systemic lupus erythematosis (SLE) or other known autoimmune diseases where this autoantibody is found in high titers. We report the unusual association of this autoantibody with recurrent early fetal demise in this case.",
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