Objectives. To study the risk factors, clinical presentations, course of the disease, investigations and management prac-tices in MS. Materials and methods. Records of 23 patients diagnosed with MS using the McDonald diagnostic criteria were ana-lysed. Outcomes. The mean age at diagnosis was 34.6±17.1 years. 17 (73.9%) patients were females. Early and late onset MS were present among 2 (8.7%) and 4 (17.4%) patients respectively. The most common symptom at diagnosis was paraes-thesia [9 (39.1%)]. Motor symptoms and sensory symptoms at the time of diagnosis were present among 9(39.1%) patients each. 20 (87%) patients had motor system involvement, 9 (39.1%) had sensory system involvement, 12 (52.2%) had cranial nerve involvement, 4 (17.4%) had sphincter dysfunction and 2 (8.7%) had cerebellar involvement. Relapsing and remit-ting MS (RRMS) were present among 18 (78.3%) patients. Oligoclonal bands were present among 17 (73.9%) patients. Vitamin D levels in the blood were found deficient among 4 (80%) out of 5 patients with available reports of the same. Juxtacortical region was the most common [9 (39.1%)] site of involvement. Steroids were used for management among majority [12 (52.2%)] of the patients. Non-pharmacological methods for management constituted only physiotherapy which was advised among 13 (56.5%) patients. Improvement in treatment outcome were seen among 19 (82.6%) pa-tients. Conclusions. Almost three fourth of the patients were females. RRMS was the most common course of the disease. Jux-tacortical region was the most common site involved. Steroids were most commonly used for management. More non-pharmacological methods need to be introduced for MS management.
|Number of pages||7|
|Journal||Romanian Journal of Neurology/ Revista Romana de Neurologie|
|Publication status||Published - 2021|
All Science Journal Classification (ASJC) codes
- Clinical Neurology