A Review on Recent Synthetic Strategies and Pharmacological Importance of 1,3-Thiazole Derivatives

Swarnagowri Nayak, Santhosh L. Gaonkar

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Thiazole is the most common heterocyclic compound in heterocyclic chemistry and in drug design. Presence of several reaction sites in the thiazole moiety extends their range of applications and leads to new solutions for challenges in synthetic and medicinal chemistry. Thiazole derivatives are widely used as bioactive agents, liquid crystals, sensors, catalysts, etc. The motivating molecular architecture of 1,3-thiazoles makes them suitable moieties for drug development. In this review, our aim is to corroborate the recent data available on various synthetic strategies and biological properties of 1,3- thiazole derivatives.

Original languageEnglish
Pages (from-to)215-238
Number of pages24
JournalMini reviews in medicinal chemistry
Volume19
Issue number3
DOIs
Publication statusPublished - 01-01-2019

All Science Journal Classification (ASJC) codes

  • Pharmacology
  • Drug Discovery

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