TY - JOUR
T1 - A Review on Recent Synthetic Strategies and Pharmacological Importance of 1,3-Thiazole Derivatives
AU - Nayak, Swarnagowri
AU - Gaonkar, Santhosh L.
PY - 2019/1/1
Y1 - 2019/1/1
N2 - Thiazole is the most common heterocyclic compound in heterocyclic chemistry and in drug design. Presence of several reaction sites in the thiazole moiety extends their range of applications and leads to new solutions for challenges in synthetic and medicinal chemistry. Thiazole derivatives are widely used as bioactive agents, liquid crystals, sensors, catalysts, etc. The motivating molecular architecture of 1,3-thiazoles makes them suitable moieties for drug development. In this review, our aim is to corroborate the recent data available on various synthetic strategies and biological properties of 1,3- thiazole derivatives.
AB - Thiazole is the most common heterocyclic compound in heterocyclic chemistry and in drug design. Presence of several reaction sites in the thiazole moiety extends their range of applications and leads to new solutions for challenges in synthetic and medicinal chemistry. Thiazole derivatives are widely used as bioactive agents, liquid crystals, sensors, catalysts, etc. The motivating molecular architecture of 1,3-thiazoles makes them suitable moieties for drug development. In this review, our aim is to corroborate the recent data available on various synthetic strategies and biological properties of 1,3- thiazole derivatives.
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U2 - 10.2174/1389557518666180816112151
DO - 10.2174/1389557518666180816112151
M3 - Article
C2 - 30112994
AN - SCOPUS:85061606487
SN - 1389-5575
VL - 19
SP - 215
EP - 238
JO - Mini-Reviews in Medicinal Chemistry
JF - Mini-Reviews in Medicinal Chemistry
IS - 3
ER -