Abstract
Background and Purpose: Resistance to fluoroquinolones and cephalosporins is a major problem with Salmonella enterica serovar Typhi and Paratyphi. An accurate determination of antibiotic susceptibility requires tests for minimum inhibitory concentration (MIC) of antibiotics. We describe a simple broth-disk method to determine the MIC of ceftriaxone on S. typhi and S. paratyphi. Materials and Methods: Sixteen strains of S. typhi and two strains each of S. paratyphi A and S. paratyphi B were used in the study. The MIC of ceftriaxone was determined using the simple broth-disk method and the conventional broth macrodilution method and the results were compared. Results: All salmonella strains were susceptible to ceftriaxone. The results of the broth-disk and the conventional broth macrodilution method were similar. Conclusion: The broth-disk method is a simple, reliable and cost-effective method to determine the MIC of ceftriaxone on S. typhi and S. paratyphi A.
| Original language | English |
|---|---|
| Pages (from-to) | 189-190 |
| Number of pages | 2 |
| Journal | Indian Journal of Pathology and Microbiology |
| Volume | 52 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - 01-04-2009 |
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All Science Journal Classification (ASJC) codes
- Pathology and Forensic Medicine
- Microbiology (medical)
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A simple broth-disk method to determine the minimum inhibitory concentration of ceftriaxone on Salmonella enterica serovar typhi and paratyphi. / Bhat, K. Gopalkrishna; Tripathy, Amruta; Rajagopal, Rajasree; Ramachandran, Sreeja.
In: Indian Journal of Pathology and Microbiology, Vol. 52, No. 2, 01.04.2009, p. 189-190.Research output: Contribution to journal › Article
TY - JOUR
T1 - A simple broth-disk method to determine the minimum inhibitory concentration of ceftriaxone on Salmonella enterica serovar typhi and paratyphi
AU - Bhat, K. Gopalkrishna
AU - Tripathy, Amruta
AU - Rajagopal, Rajasree
AU - Ramachandran, Sreeja
PY - 2009/4/1
Y1 - 2009/4/1
N2 - Background and Purpose: Resistance to fluoroquinolones and cephalosporins is a major problem with Salmonella enterica serovar Typhi and Paratyphi. An accurate determination of antibiotic susceptibility requires tests for minimum inhibitory concentration (MIC) of antibiotics. We describe a simple broth-disk method to determine the MIC of ceftriaxone on S. typhi and S. paratyphi. Materials and Methods: Sixteen strains of S. typhi and two strains each of S. paratyphi A and S. paratyphi B were used in the study. The MIC of ceftriaxone was determined using the simple broth-disk method and the conventional broth macrodilution method and the results were compared. Results: All salmonella strains were susceptible to ceftriaxone. The results of the broth-disk and the conventional broth macrodilution method were similar. Conclusion: The broth-disk method is a simple, reliable and cost-effective method to determine the MIC of ceftriaxone on S. typhi and S. paratyphi A.
AB - Background and Purpose: Resistance to fluoroquinolones and cephalosporins is a major problem with Salmonella enterica serovar Typhi and Paratyphi. An accurate determination of antibiotic susceptibility requires tests for minimum inhibitory concentration (MIC) of antibiotics. We describe a simple broth-disk method to determine the MIC of ceftriaxone on S. typhi and S. paratyphi. Materials and Methods: Sixteen strains of S. typhi and two strains each of S. paratyphi A and S. paratyphi B were used in the study. The MIC of ceftriaxone was determined using the simple broth-disk method and the conventional broth macrodilution method and the results were compared. Results: All salmonella strains were susceptible to ceftriaxone. The results of the broth-disk and the conventional broth macrodilution method were similar. Conclusion: The broth-disk method is a simple, reliable and cost-effective method to determine the MIC of ceftriaxone on S. typhi and S. paratyphi A.
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U2 - 10.4103/0377-4929.48913
DO - 10.4103/0377-4929.48913
M3 - Article
VL - 52
SP - 189
EP - 190
JO - Indian Journal of Pathology and Microbiology
JF - Indian Journal of Pathology and Microbiology
SN - 0377-4929
IS - 2
ER -