Purpose: To study the effect of ASAP solution (10 ppm silver solution) on pathogenic bacteria and Candida albicans. Materials and methods: The bacteria studied included Methicillin-resistant Staphylococcus aureus, Vancomycin-resistant Enterococcus faecalis, drug-resistant Escherichia coli, ESBL producing Klebsiella pneumoniae, drug-resistant Pseudomonas aeruginosa, Salmonella typhi, and Shigella flexneri. All bacteria were isolated from clinical samples. One strain of Candida albicans was also used. The inhibitory and microbicidal effect of ASAP were determined by broth dilution and suspension test. S. aureus ATCC 25,923 and E. coli ATCC 25,922 were used as controls. Results: ASAP solution inhibited and killed all bacteria and candida used in the study irrespective of the Gram reaction. Bacteria were more susceptible than candida. Contact time of 30 min - 60 min was needed to kill bacteria. C. albicans was killed after 120 min of exposure to ASAP. Conclusion: ASAP is effective in killing drug-resistant bacteria and C. albicans. This property of ASAP may be explored in the treatment of drug resistant infections.
|Number of pages||3|
|Journal||Journal, Indian Academy of Clinical Medicine|
|Publication status||Published - 01-2009|
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