Acute haematologic reaction: Drug or bug?

A. Avinash, Sushil Kiran Kunder, Sharath Madhyastha, Raviraj Acharya, Vinaya Gopalaswamy, Navin Patil, Anurag Pathak, M. N. Vinay

Research output: Contribution to journalArticle

Abstract

β-lactams are known to cause haematologic reactions. Cefoperazone is one such β-lactam that is commonly combined with a β-lactamase inhibitor, sulbactam. A review of the available literature suggests that cefoperazone can cause or precipitate haematologic reactions, including anaemia, leucopenia, thrombocytopenia and hypoprothrombinemia. Similarly, Escherichia coli (E. coli) is a commonly encountered organism associated with urinary tract infections and urosepsis, which can also present in a similar. This case report is a description of an elderly patient who harboured E. coli, and was also given cefoperazone-sulbactam, and later developed haematologic reactions.

Original languageEnglish
Pages (from-to)1884-1886
Number of pages3
JournalResearch Journal of Pharmaceutical, Biological and Chemical Sciences
Volume7
Issue number4
Publication statusPublished - 01-07-2016

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Cefoperazone
Sulbactam
Lactams
Escherichia coli
Hypoprothrombinemias
Pharmaceutical Preparations
Leukopenia
Urinary Tract Infections
Thrombocytopenia
Anemia
Precipitates

All Science Journal Classification (ASJC) codes

  • Biochemistry, Genetics and Molecular Biology(all)
  • Pharmacology, Toxicology and Pharmaceutics(all)

Cite this

Avinash, A., Kunder, S. K., Madhyastha, S., Acharya, R., Gopalaswamy, V., Patil, N., ... Vinay, M. N. (2016). Acute haematologic reaction: Drug or bug? Research Journal of Pharmaceutical, Biological and Chemical Sciences, 7(4), 1884-1886.
Avinash, A. ; Kunder, Sushil Kiran ; Madhyastha, Sharath ; Acharya, Raviraj ; Gopalaswamy, Vinaya ; Patil, Navin ; Pathak, Anurag ; Vinay, M. N. / Acute haematologic reaction : Drug or bug?. In: Research Journal of Pharmaceutical, Biological and Chemical Sciences. 2016 ; Vol. 7, No. 4. pp. 1884-1886.
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Avinash, A, Kunder, SK, Madhyastha, S, Acharya, R, Gopalaswamy, V, Patil, N, Pathak, A & Vinay, MN 2016, 'Acute haematologic reaction: Drug or bug?', Research Journal of Pharmaceutical, Biological and Chemical Sciences, vol. 7, no. 4, pp. 1884-1886.

Acute haematologic reaction : Drug or bug? / Avinash, A.; Kunder, Sushil Kiran; Madhyastha, Sharath; Acharya, Raviraj; Gopalaswamy, Vinaya; Patil, Navin; Pathak, Anurag; Vinay, M. N.

In: Research Journal of Pharmaceutical, Biological and Chemical Sciences, Vol. 7, No. 4, 01.07.2016, p. 1884-1886.

Research output: Contribution to journalArticle

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AU - Avinash, A.

AU - Kunder, Sushil Kiran

AU - Madhyastha, Sharath

AU - Acharya, Raviraj

AU - Gopalaswamy, Vinaya

AU - Patil, Navin

AU - Pathak, Anurag

AU - Vinay, M. N.

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Avinash A, Kunder SK, Madhyastha S, Acharya R, Gopalaswamy V, Patil N et al. Acute haematologic reaction: Drug or bug? Research Journal of Pharmaceutical, Biological and Chemical Sciences. 2016 Jul 1;7(4):1884-1886.