Alanine peak in central neurocytomas on proton MR spectroscopy

T. Krishnamoorthy, V.V. Radhakrishnan, B. Thomas, E.R. Jeyadevan, G. Menon, S. Nair

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

Introduction: We present three consecutive patients with central neurocytoma in whom proton MRS demonstrated the presence of alanine. Materials and methods: Three patients in the age range 24 to 30 years underwent MRI and proton MRS using a 1.5-T system. MRS was performed with the multivoxel PRESS sequence. All three patients underwent surgery and the diagnosis of central neurocytoma was established by histopathological examination and immunostaining. Results: With an echotime of 135 ms glycine, high choline, small NAA and alanine were observed in all three patients. Conclusion: Alanine may be observed in central neurocytomas as it is in meningiomas. Other spectral peaks such as those for glycine and NAA should help to identify this tumor correctly. © Springer-Verlag 2007.
Original languageEnglish
Pages (from-to)551-554
Number of pages4
JournalNeuroradiology
Volume49
Issue number7
DOIs
Publication statusPublished - 2007

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Neurocytoma
Alanine
Protons
Magnetic Resonance Spectroscopy
Glycine
Meningioma
Choline
Neoplasms

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Krishnamoorthy, T., Radhakrishnan, V. V., Thomas, B., Jeyadevan, E. R., Menon, G., & Nair, S. (2007). Alanine peak in central neurocytomas on proton MR spectroscopy. Neuroradiology, 49(7), 551-554. https://doi.org/10.1007/s00234-007-0224-2
Krishnamoorthy, T. ; Radhakrishnan, V.V. ; Thomas, B. ; Jeyadevan, E.R. ; Menon, G. ; Nair, S. / Alanine peak in central neurocytomas on proton MR spectroscopy. In: Neuroradiology. 2007 ; Vol. 49, No. 7. pp. 551-554.
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Krishnamoorthy, T, Radhakrishnan, VV, Thomas, B, Jeyadevan, ER, Menon, G & Nair, S 2007, 'Alanine peak in central neurocytomas on proton MR spectroscopy', Neuroradiology, vol. 49, no. 7, pp. 551-554. https://doi.org/10.1007/s00234-007-0224-2

Alanine peak in central neurocytomas on proton MR spectroscopy. / Krishnamoorthy, T.; Radhakrishnan, V.V.; Thomas, B.; Jeyadevan, E.R.; Menon, G.; Nair, S.

In: Neuroradiology, Vol. 49, No. 7, 2007, p. 551-554.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Alanine peak in central neurocytomas on proton MR spectroscopy

AU - Krishnamoorthy, T.

AU - Radhakrishnan, V.V.

AU - Thomas, B.

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AU - Menon, G.

AU - Nair, S.

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N2 - Introduction: We present three consecutive patients with central neurocytoma in whom proton MRS demonstrated the presence of alanine. Materials and methods: Three patients in the age range 24 to 30 years underwent MRI and proton MRS using a 1.5-T system. MRS was performed with the multivoxel PRESS sequence. All three patients underwent surgery and the diagnosis of central neurocytoma was established by histopathological examination and immunostaining. Results: With an echotime of 135 ms glycine, high choline, small NAA and alanine were observed in all three patients. Conclusion: Alanine may be observed in central neurocytomas as it is in meningiomas. Other spectral peaks such as those for glycine and NAA should help to identify this tumor correctly. © Springer-Verlag 2007.

AB - Introduction: We present three consecutive patients with central neurocytoma in whom proton MRS demonstrated the presence of alanine. Materials and methods: Three patients in the age range 24 to 30 years underwent MRI and proton MRS using a 1.5-T system. MRS was performed with the multivoxel PRESS sequence. All three patients underwent surgery and the diagnosis of central neurocytoma was established by histopathological examination and immunostaining. Results: With an echotime of 135 ms glycine, high choline, small NAA and alanine were observed in all three patients. Conclusion: Alanine may be observed in central neurocytomas as it is in meningiomas. Other spectral peaks such as those for glycine and NAA should help to identify this tumor correctly. © Springer-Verlag 2007.

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Krishnamoorthy T, Radhakrishnan VV, Thomas B, Jeyadevan ER, Menon G, Nair S. Alanine peak in central neurocytomas on proton MR spectroscopy. Neuroradiology. 2007;49(7):551-554. https://doi.org/10.1007/s00234-007-0224-2