Adult albino rats of Wistar strain (200 to 250 g) were lesioned at the nucleus accumbens (Acb) either is the shell area (Acbsh) or in the core area (Acbc). The rats were offered a choice of water and 0.2 per cent saccharine or water and 12 per cent sucrose solution. During the prelesion period, the rats preferred water to the sweet tasting fluids. The Acbc lesion shifted the preference to saccharine from water, but rats with the same lesion consumed equal quantities of sucrose and water. On the other hand, lesion of the Acbsh increased the water intake when paired with either sucrose or saccharine. Food intake was also increased in this lesioned group. The results suggest that the Acbc area appears to participate in the mediation of taste of food while the Acbsh area probably regulates feeding behaviour based on the nutritional value of food substances.
|Number of pages||6|
|Journal||Indian Journal of Medical Research|
|Publication status||Published - 02-11-1998|
All Science Journal Classification (ASJC) codes
- Biochemistry, Genetics and Molecular Biology(all)