Amino acid conjugated chitosan nanoparticles for the brain targeting of a model dipeptidyl peptidase-4 inhibitor

Medicine & Life Sciences

• saxagliptin 89%
• Dipeptidyl-Peptidase IV Inhibitors 72%
• Chitosan 60%
• Nanoparticles 48%
• Amino Acids 38%
• Brain 27%
• Blood-Brain Barrier 13%
• rhodamine B 10%
• Carbodiimides 10%
• Drug Repositioning 9%
• Valine 8%
• Enzyme Inhibitors 7%
• Fluorescent Dyes 7%
• Particle Size 7%
• Permeability 5%
• Blood Glucose 5%
• Alzheimer Disease 5%
• Pharmacokinetics 5%

Chemical Compounds

• Saxagliptin 100%
• Dipeptidyl Peptidase IV Inhibitor 86%
• Chitosan 45%
• Nanoparticle 27%
• Acid 19%
• Plasma 12%
• Purity 10%
• Peak Plasma Concentration 9%
• Enzyme Inhibitor 7%
• Carbodiimide 7%
• Drug 7%
• Fluorescent Dye 7%
• Rhodamine B 6%
• Amount 5%
• Permeability 5%
• Pharmacokinetics 5%