An autopsy study of coronary atherosclerosis and its relation to anthropometric measurements/indices of overweight and obesity in men

Prateek Rastogi, Denver S. Pinto, Mukta R. Pai, Tanuj Kanchan

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Atherosclerosis accounts for a large proportion of cardiovascular system associated morbidity and mortality. The present autopsy based study is aimed to study the correlation between coronary atherosclerosis and anthropometric measurements/indices of overweight and obesity such as; Waist Circumference (WC), Hip Circumference (HC), Body Mass Index (BMI), and Waist Hip Ratio (WHR) in men from southern India. The present research also analyses the correlation between anthropometric measurements/indices of overweight and obesity in men with number of coronaries affected with atherosclerosis in individuals. The study included 50 autopsies conducted in the Government District Wenlock Hospital, Mangalore during March and September 2008. The heart was dissected following standard autopsy protocol and a 5 cm section of the right coronary artery (RCA) in the atrio-ventricular groove from its origin, a 5 cm segment of the left anterior descending artery (LADA) distal to the origin of the circumflex artery, but including the region of origin of the circumflex branch and left coronary artery (LCA) from its origin till the circumflex branch were excised, dissected out, fixed in 10% formalin, marked for identification and sent for histopathological analysis. The study shows a positive correlation of WC and WHR with atherosclerotic changes in the RCA. The number of arteries affected with atherosclerosis is found to be well correlated with WC, BMI and WHR. The study confirms an association between anthropometric measurements/indices of obesity, grade of atherosclerosis in the RCA and the number of arteries affected with atherosclerosis. Anthropometric measurements/indices of obesity can be an effective means to identify high risk cases of atherosclerosis at an early stage that can be effective in reducing the associated cardiac morbidity and mortality.

Original languageEnglish
Pages (from-to)12-17
Number of pages6
JournalJournal of Forensic and Legal Medicine
Volume19
Issue number1
DOIs
Publication statusPublished - 01-01-2012
Externally publishedYes

Fingerprint

Coronary Artery Disease
Autopsy
Atherosclerosis
Obesity
Waist-Hip Ratio
Coronary Vessels
Waist Circumference
Arteries
morbidity
Body Mass Index
mortality
Morbidity
District Hospitals
Mortality
Cardiovascular System
Formaldehyde
Hip
India
district
present

All Science Journal Classification (ASJC) codes

  • Pathology and Forensic Medicine
  • Law

Cite this

@article{07871a468eb741d5bdf79fdc66e4d4bc,
title = "An autopsy study of coronary atherosclerosis and its relation to anthropometric measurements/indices of overweight and obesity in men",
abstract = "Atherosclerosis accounts for a large proportion of cardiovascular system associated morbidity and mortality. The present autopsy based study is aimed to study the correlation between coronary atherosclerosis and anthropometric measurements/indices of overweight and obesity such as; Waist Circumference (WC), Hip Circumference (HC), Body Mass Index (BMI), and Waist Hip Ratio (WHR) in men from southern India. The present research also analyses the correlation between anthropometric measurements/indices of overweight and obesity in men with number of coronaries affected with atherosclerosis in individuals. The study included 50 autopsies conducted in the Government District Wenlock Hospital, Mangalore during March and September 2008. The heart was dissected following standard autopsy protocol and a 5 cm section of the right coronary artery (RCA) in the atrio-ventricular groove from its origin, a 5 cm segment of the left anterior descending artery (LADA) distal to the origin of the circumflex artery, but including the region of origin of the circumflex branch and left coronary artery (LCA) from its origin till the circumflex branch were excised, dissected out, fixed in 10{\%} formalin, marked for identification and sent for histopathological analysis. The study shows a positive correlation of WC and WHR with atherosclerotic changes in the RCA. The number of arteries affected with atherosclerosis is found to be well correlated with WC, BMI and WHR. The study confirms an association between anthropometric measurements/indices of obesity, grade of atherosclerosis in the RCA and the number of arteries affected with atherosclerosis. Anthropometric measurements/indices of obesity can be an effective means to identify high risk cases of atherosclerosis at an early stage that can be effective in reducing the associated cardiac morbidity and mortality.",
author = "Prateek Rastogi and Pinto, {Denver S.} and Pai, {Mukta R.} and Tanuj Kanchan",
year = "2012",
month = "1",
day = "1",
doi = "10.1016/j.jflm.2011.09.003",
language = "English",
volume = "19",
pages = "12--17",
journal = "Journal of Forensic and Legal Medicine",
issn = "1752-928X",
publisher = "Churchill Livingstone",
number = "1",

}

An autopsy study of coronary atherosclerosis and its relation to anthropometric measurements/indices of overweight and obesity in men. / Rastogi, Prateek; Pinto, Denver S.; Pai, Mukta R.; Kanchan, Tanuj.

In: Journal of Forensic and Legal Medicine, Vol. 19, No. 1, 01.01.2012, p. 12-17.

Research output: Contribution to journalArticle

TY - JOUR

T1 - An autopsy study of coronary atherosclerosis and its relation to anthropometric measurements/indices of overweight and obesity in men

AU - Rastogi, Prateek

AU - Pinto, Denver S.

AU - Pai, Mukta R.

AU - Kanchan, Tanuj

PY - 2012/1/1

Y1 - 2012/1/1

N2 - Atherosclerosis accounts for a large proportion of cardiovascular system associated morbidity and mortality. The present autopsy based study is aimed to study the correlation between coronary atherosclerosis and anthropometric measurements/indices of overweight and obesity such as; Waist Circumference (WC), Hip Circumference (HC), Body Mass Index (BMI), and Waist Hip Ratio (WHR) in men from southern India. The present research also analyses the correlation between anthropometric measurements/indices of overweight and obesity in men with number of coronaries affected with atherosclerosis in individuals. The study included 50 autopsies conducted in the Government District Wenlock Hospital, Mangalore during March and September 2008. The heart was dissected following standard autopsy protocol and a 5 cm section of the right coronary artery (RCA) in the atrio-ventricular groove from its origin, a 5 cm segment of the left anterior descending artery (LADA) distal to the origin of the circumflex artery, but including the region of origin of the circumflex branch and left coronary artery (LCA) from its origin till the circumflex branch were excised, dissected out, fixed in 10% formalin, marked for identification and sent for histopathological analysis. The study shows a positive correlation of WC and WHR with atherosclerotic changes in the RCA. The number of arteries affected with atherosclerosis is found to be well correlated with WC, BMI and WHR. The study confirms an association between anthropometric measurements/indices of obesity, grade of atherosclerosis in the RCA and the number of arteries affected with atherosclerosis. Anthropometric measurements/indices of obesity can be an effective means to identify high risk cases of atherosclerosis at an early stage that can be effective in reducing the associated cardiac morbidity and mortality.

AB - Atherosclerosis accounts for a large proportion of cardiovascular system associated morbidity and mortality. The present autopsy based study is aimed to study the correlation between coronary atherosclerosis and anthropometric measurements/indices of overweight and obesity such as; Waist Circumference (WC), Hip Circumference (HC), Body Mass Index (BMI), and Waist Hip Ratio (WHR) in men from southern India. The present research also analyses the correlation between anthropometric measurements/indices of overweight and obesity in men with number of coronaries affected with atherosclerosis in individuals. The study included 50 autopsies conducted in the Government District Wenlock Hospital, Mangalore during March and September 2008. The heart was dissected following standard autopsy protocol and a 5 cm section of the right coronary artery (RCA) in the atrio-ventricular groove from its origin, a 5 cm segment of the left anterior descending artery (LADA) distal to the origin of the circumflex artery, but including the region of origin of the circumflex branch and left coronary artery (LCA) from its origin till the circumflex branch were excised, dissected out, fixed in 10% formalin, marked for identification and sent for histopathological analysis. The study shows a positive correlation of WC and WHR with atherosclerotic changes in the RCA. The number of arteries affected with atherosclerosis is found to be well correlated with WC, BMI and WHR. The study confirms an association between anthropometric measurements/indices of obesity, grade of atherosclerosis in the RCA and the number of arteries affected with atherosclerosis. Anthropometric measurements/indices of obesity can be an effective means to identify high risk cases of atherosclerosis at an early stage that can be effective in reducing the associated cardiac morbidity and mortality.

UR - http://www.scopus.com/inward/record.url?scp=82955237340&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=82955237340&partnerID=8YFLogxK

U2 - 10.1016/j.jflm.2011.09.003

DO - 10.1016/j.jflm.2011.09.003

M3 - Article

VL - 19

SP - 12

EP - 17

JO - Journal of Forensic and Legal Medicine

JF - Journal of Forensic and Legal Medicine

SN - 1752-928X

IS - 1

ER -