Introduction: The aim of the study is to assess the knowledge and practice skills of home-based colostomy caregivers of children with a colostomy. The objective of the study was to assess the effectiveness of video teaching module on colostomy care among home-based colostomy caregivers. Method: A quasi-experimental study design and 30 samples were adopted. The samples selected by the purposive sampling technique those were fulfilled the sample criteria. Demographic and structured knowledge questionnaires were used for the data collection. Result: Descriptive and inferential statistics were used for data analysis by using SPSS software version 16.0. Out of 30 samples, demographic variables, 23 (76.6%) of the participants are of age between 21 and 30 years, 21 (70%) were housewives, 23 (76.6%) were mothers, 16 (53.4%) completed higher secondary, and 23 (76.6%) have monthly family income of INR 5001–10000. The majority of the children with a colostomy were toddler 22 (73.3%), gender ratio was equal, 27 (90%) are of Hindu religion, and 29 (96.7%) undergone colostomy. Knowledge score was divided based on percentage. Good knowledge scores in pre- and posttest are 0 and 29 (96.5%); moderate knowledge in pre- and posttest, 9 (30.5%) and 1 (3.3%); and poor knowledge in pre- vs posttest, 21(70%) and 0, respectively. Inferential statistics evaluated colostomy care video intervention. Knowledge was assessed by paired t test, − 19.607 (p < 0.05); similarly, practice skill assessed by Wilcoxon signed-rank was (z) − 4.716 (p < 0.01). Conclusion: Colostomy care video was a powerful tool to enhance primary caregivers’ confidence, colostomy care skills, and attitude.
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