An identity based pharmacognostical profile of folium Annona squamosa

C.D. Kumar, K. Rajendran, R. Lobo, A. Shirwaikar

Research output: Contribution to journalArticle

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Abstract

The leaves of Annona squamosa Linn. (Annonaceae), commonly called as custard apple, are popularly used for the treatment of diabetes by various tribes in India. The leaves are also used for their powerful insecticidal activity, especially for destroying lice. This paper presents a detailed pharmacognostical study of the crude drug, folium Annona squamosa. The samples were studied using procedures of light, confocal microscopy, WHO recommended physico-chemical determinations and authentic phytochemical procedures. The physicochemical, morphological and histological parameters presented in this paper may be proposed as parameters to establish the authenticity of Annona squamosa leaf and may possibly help to differentiate the drug from its adulterants.
Original languageEnglish
Pages (from-to)213-219
Number of pages7
JournalNatural Product Sciences
Volume11
Issue number4
Publication statusPublished - 2005

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Annona
Confocal microscopy
Phytochemicals
Medical problems
Annonaceae
Pharmaceutical Preparations
Phthiraptera
Malus
Confocal Microscopy
India
Light

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Kumar, C. D., Rajendran, K., Lobo, R., & Shirwaikar, A. (2005). An identity based pharmacognostical profile of folium Annona squamosa. Natural Product Sciences, 11(4), 213-219.
Kumar, C.D. ; Rajendran, K. ; Lobo, R. ; Shirwaikar, A. / An identity based pharmacognostical profile of folium Annona squamosa. In: Natural Product Sciences. 2005 ; Vol. 11, No. 4. pp. 213-219.
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abstract = "The leaves of Annona squamosa Linn. (Annonaceae), commonly called as custard apple, are popularly used for the treatment of diabetes by various tribes in India. The leaves are also used for their powerful insecticidal activity, especially for destroying lice. This paper presents a detailed pharmacognostical study of the crude drug, folium Annona squamosa. The samples were studied using procedures of light, confocal microscopy, WHO recommended physico-chemical determinations and authentic phytochemical procedures. The physicochemical, morphological and histological parameters presented in this paper may be proposed as parameters to establish the authenticity of Annona squamosa leaf and may possibly help to differentiate the drug from its adulterants.",
author = "C.D. Kumar and K. Rajendran and R. Lobo and A. Shirwaikar",
note = "Export Date: 10 November 2017 CODEN: NPSCF Correspondence Address: Shirwaikar, A.; Department of Pharmacognosy, Manipal College of Pharmaceutical Sciences, Manipal-576 104, India; email: annieshirwaikar@yahoo.com References: Araya, H., Sahai, M., Singh, S., Singh, A.K., Yoshida, M., Hara, N., Fugimoto, Y., Squamocin-O1 and squamocin-O2, new adjacent bis-tetrahydrofuran acetogenins from the seeds of Annona squamosa (2002) Phytochemistry, 61, pp. 999-1004; Atique, A., Iqbal, M., Ghouse, A.K.M., Use of Annona squamosa and Piper nigrum against diabetes (1985) Fitoterapia, 56, p. 190; Atta-Ur-Rahman, Zaman, K., Medicinal plants with hypoglycemic activity (1989) J. Ethnopharmacol., 26, pp. 1-55; Bhakuni, D.S., Tewari, S., Dhar, M.M., Aporphine alkaloids of Annona squamosa (1972) Phytochemistry, 11, pp. 1819-1822; Bhaumik, P.K., Mukherjee, B., Juneau, J.P., Bhacca, N.S., Mukherjee, R., Alkaloids from leaves of Annona squamosa (1979) Phytochemistry, 18, pp. 1584-1586; Brain, K.R., Turner, T.D., (1975) The Practical Evaluation of Phytopharmaceuticals, pp. 4-9. , Wright-Scientechnica, Bristol; Brain, K.R., Turner, T.D., (1975) The Practical Evaluation of Phytopharmaceuticals, pp. 36-45. , Wright-Scientechnica, Bristol; Chase, C.R., Pratt, R.J., Fluorescence of powdered vegetable drugs with particular reference to development of a system of identification (1949) J. Am. Pharmacol. Assoc., 38, p. 32; Evans, W.C., (2003) Trease and Evans Pharmacognosy, 15th Edn., pp. 545-547. , Saunders, London; Fugimoto, Y., Murasaki, C., Kakinuma, K., Fguchi, T., Ikekawa, N., Furuya, M., Hirayama, K., Gupta, Y.K., Squamostatin-A: Unprecedented bis-tetrahydrofuran acetogenin from Annona squamosa (1990) Tetra. Lett., 31, pp. 535-538; Gupta, R.K., Kesari, A.N., Murthy, P.S., Chandra, R., Tandon, V., Watal, G., Hypoglycemic and antidiabetic effect of ethanolic extract of leaves of Annona squamosa L. in experimental animals (2005) J. Ethnopharmacol., 99, pp. 75-81; Gupta, R.K., Kesari, A.N., Watal, G., Murthy, P.S., Chandra, R., Maithal, K., Tandon, V., Hypoglycemic and antidiabetic effect of aqueous extract of leaves of Annona squamosa L. in experimental animal (2005) Curr. Sci., 88, pp. 1244-1254; Hopp, D.C., Alali, F.Q., Gu, Z.M., McLaughlin, J.L., Three new bioactive bis-adjacent THF-ring acetogenins from the bark of Annona squamosa (1998) Bioorg. Med. Chem., 6, pp. 569-575; Hopp, D.C., Zeng, L., Gu, Z., McLaughlin, J.L., Squamotacin: An annonaceous acetogenin with cytotoxic selectivity for the human prostate tumor cell line (PC-3) (1996) J. Nat. Prod., 59, pp. 97-99; (1996) Indian Pharmacopoeia, 4th Edn., 2, pp. A53-A54. , Government of India, Ministry of Health and Welfare, Controller of Publications, New Delhi; Johansen, D.A., (1940) Plant Microtechnique, p. 182. , McGraw Hill, New York; Kirtikar, K.R., Basu, B.D., (1975) Indian Medicinal Plants, Vol. I, 2nd Ed., 1, pp. 66-67. , M/s Periodical Experts, Delhi; Kokate, C.K., (1986) Practical Pharmacognosy, 1st Ed., pp. 15-30. , Vallabh Prakashan, New Delhi; Kokate, C.K., (1986) Practical Pharmacognosy, 1st Ed., p. 111. , Vallabh Prakashan, New Delhi; Kokoski, J., Kokoski, R., Slama, F.J., Fluorescence of powdered vegetable drugs under ultraviolet radiation (1958) J. Am. Pharmacol. Assoc., 47, p. 715; Li, X.H., Hui, Y.H., Rupprecht, J.K., Liu, Y.M., Wood, K.V., Smith, D.L., Chang, C.J., McLaughlin, J.L., Bullatacin, bullatacinone and squamone, a new bioactive acetogenin from the bark of Annona squamosa (1990) J. Nat. Prod., 53, pp. 81-86; Morita, H., Sato, Y., Chan, K.L., Choo, C.Y., Itokawa, H., Takeya, K., Kobayashi, J., Samoquasine A, a benzoquinoline alkaloid from the seeds of Annona squamosa (2000) J. Nat. Prod., 63, pp. 1707-1708; Morita, H., Sato, Y., Kobayashi, J., Cyclosquamosins A-G, cyclic peptides from the seeds of Annona squamosa (1999) Tetrahedron, 55, pp. 7509-7518; Mukerjea, T.D., Govind, R., Studies on indigenous insecticidal plants: Part II-Annona squamosa (1958) J. Sci. Industr. Res., 17 C, pp. 9-15; Nadkarni, A.K., (2000) Indian Materia Medico, 1, p. 116. , Popular Prakashan Ltd., Mumbai, India; Nonfon, M., Lieb, F., Moeschler, H., Wendisch, D., Four annonins from Annona squamosa (1990) Phytochemistry, 29, pp. 1951-1954; Satyavati, G.V., Raina, M.K., Sharma, M., (1976) Medicinal Plants of India, 1, pp. 75-76. , ICMR Publication, New Delhi; Shirwaikar, A., Rajendran, K., Dinesh Kumar, C., Bodla, R.G., Antidiabetic activity of aqueous leaf extract of Annona squamosa in streptozotocin-nicotinamide type 2 diabetic rats (2004) J. Ethnopharmacol., 91, pp. 171-175; Shirwaikar, A., Rajendran, K., Dinesh Kumar, C., Oral antidiabetic activity of Annona squamosa leaf alcohol extract in NIDDM rats (2004) Pharm. Biol., 42, pp. 30-35; Sunanda, P., Anand, K., Possible amelioration of hyperthyroidism by the leaf extract of Annona squamosa (2003) Curr. Sci., 84, pp. 1402-1404; Topno, K.K., Plants used by tribals of Chotanagpur against diabetes (1997) Botanica, 47, p. 99; Trimurti, N., Alkaloids from Annona squamosa leaves (1924) J. Ind. Inst. Sci., 7, p. 232; Warrier, P.K., Nambiar, V.P.K., Raman Kutty, C., (1996) Indian Medicinal Plants, 1, p. 160. , Orient Longman, Hyderabad, India; (1992) Quality Control Methods for Medicinal Plant Materials, p. 9. , Organisation Mondiale De La Sante, Geneva; Yang, Y.L., Chang, F.R., Wu, Y.C., Total synthesis of 3,4-dihydro benzo(h) quinazolin-4-one and structure elucidation of perolidine and samoquasine A (2003) Tetra. Lett., 44, pp. 319-322; Yoganarasimhan, S., (2000) Medicinal Plants of India-Tamilnadu, 2, p. 48. , Cyber Media, Bangalore",
year = "2005",
language = "English",
volume = "11",
pages = "213--219",
journal = "Natural Product Sciences",
issn = "1226-3907",
publisher = "Korean Society of Pharmacognosy",
number = "4",

}

Kumar, CD, Rajendran, K, Lobo, R & Shirwaikar, A 2005, 'An identity based pharmacognostical profile of folium Annona squamosa', Natural Product Sciences, vol. 11, no. 4, pp. 213-219.

An identity based pharmacognostical profile of folium Annona squamosa. / Kumar, C.D.; Rajendran, K.; Lobo, R.; Shirwaikar, A.

In: Natural Product Sciences, Vol. 11, No. 4, 2005, p. 213-219.

Research output: Contribution to journalArticle

TY - JOUR

T1 - An identity based pharmacognostical profile of folium Annona squamosa

AU - Kumar, C.D.

AU - Rajendran, K.

AU - Lobo, R.

AU - Shirwaikar, A.

N1 - Export Date: 10 November 2017 CODEN: NPSCF Correspondence Address: Shirwaikar, A.; Department of Pharmacognosy, Manipal College of Pharmaceutical Sciences, Manipal-576 104, India; email: annieshirwaikar@yahoo.com References: Araya, H., Sahai, M., Singh, S., Singh, A.K., Yoshida, M., Hara, N., Fugimoto, Y., Squamocin-O1 and squamocin-O2, new adjacent bis-tetrahydrofuran acetogenins from the seeds of Annona squamosa (2002) Phytochemistry, 61, pp. 999-1004; Atique, A., Iqbal, M., Ghouse, A.K.M., Use of Annona squamosa and Piper nigrum against diabetes (1985) Fitoterapia, 56, p. 190; Atta-Ur-Rahman, Zaman, K., Medicinal plants with hypoglycemic activity (1989) J. Ethnopharmacol., 26, pp. 1-55; Bhakuni, D.S., Tewari, S., Dhar, M.M., Aporphine alkaloids of Annona squamosa (1972) Phytochemistry, 11, pp. 1819-1822; Bhaumik, P.K., Mukherjee, B., Juneau, J.P., Bhacca, N.S., Mukherjee, R., Alkaloids from leaves of Annona squamosa (1979) Phytochemistry, 18, pp. 1584-1586; Brain, K.R., Turner, T.D., (1975) The Practical Evaluation of Phytopharmaceuticals, pp. 4-9. , Wright-Scientechnica, Bristol; Brain, K.R., Turner, T.D., (1975) The Practical Evaluation of Phytopharmaceuticals, pp. 36-45. , Wright-Scientechnica, Bristol; Chase, C.R., Pratt, R.J., Fluorescence of powdered vegetable drugs with particular reference to development of a system of identification (1949) J. Am. Pharmacol. Assoc., 38, p. 32; Evans, W.C., (2003) Trease and Evans Pharmacognosy, 15th Edn., pp. 545-547. , Saunders, London; Fugimoto, Y., Murasaki, C., Kakinuma, K., Fguchi, T., Ikekawa, N., Furuya, M., Hirayama, K., Gupta, Y.K., Squamostatin-A: Unprecedented bis-tetrahydrofuran acetogenin from Annona squamosa (1990) Tetra. Lett., 31, pp. 535-538; Gupta, R.K., Kesari, A.N., Murthy, P.S., Chandra, R., Tandon, V., Watal, G., Hypoglycemic and antidiabetic effect of ethanolic extract of leaves of Annona squamosa L. in experimental animals (2005) J. Ethnopharmacol., 99, pp. 75-81; Gupta, R.K., Kesari, A.N., Watal, G., Murthy, P.S., Chandra, R., Maithal, K., Tandon, V., Hypoglycemic and antidiabetic effect of aqueous extract of leaves of Annona squamosa L. in experimental animal (2005) Curr. Sci., 88, pp. 1244-1254; Hopp, D.C., Alali, F.Q., Gu, Z.M., McLaughlin, J.L., Three new bioactive bis-adjacent THF-ring acetogenins from the bark of Annona squamosa (1998) Bioorg. Med. Chem., 6, pp. 569-575; Hopp, D.C., Zeng, L., Gu, Z., McLaughlin, J.L., Squamotacin: An annonaceous acetogenin with cytotoxic selectivity for the human prostate tumor cell line (PC-3) (1996) J. Nat. Prod., 59, pp. 97-99; (1996) Indian Pharmacopoeia, 4th Edn., 2, pp. A53-A54. , Government of India, Ministry of Health and Welfare, Controller of Publications, New Delhi; Johansen, D.A., (1940) Plant Microtechnique, p. 182. , McGraw Hill, New York; Kirtikar, K.R., Basu, B.D., (1975) Indian Medicinal Plants, Vol. I, 2nd Ed., 1, pp. 66-67. , M/s Periodical Experts, Delhi; Kokate, C.K., (1986) Practical Pharmacognosy, 1st Ed., pp. 15-30. , Vallabh Prakashan, New Delhi; Kokate, C.K., (1986) Practical Pharmacognosy, 1st Ed., p. 111. , Vallabh Prakashan, New Delhi; Kokoski, J., Kokoski, R., Slama, F.J., Fluorescence of powdered vegetable drugs under ultraviolet radiation (1958) J. Am. Pharmacol. Assoc., 47, p. 715; Li, X.H., Hui, Y.H., Rupprecht, J.K., Liu, Y.M., Wood, K.V., Smith, D.L., Chang, C.J., McLaughlin, J.L., Bullatacin, bullatacinone and squamone, a new bioactive acetogenin from the bark of Annona squamosa (1990) J. Nat. Prod., 53, pp. 81-86; Morita, H., Sato, Y., Chan, K.L., Choo, C.Y., Itokawa, H., Takeya, K., Kobayashi, J., Samoquasine A, a benzoquinoline alkaloid from the seeds of Annona squamosa (2000) J. Nat. Prod., 63, pp. 1707-1708; Morita, H., Sato, Y., Kobayashi, J., Cyclosquamosins A-G, cyclic peptides from the seeds of Annona squamosa (1999) Tetrahedron, 55, pp. 7509-7518; Mukerjea, T.D., Govind, R., Studies on indigenous insecticidal plants: Part II-Annona squamosa (1958) J. Sci. Industr. Res., 17 C, pp. 9-15; Nadkarni, A.K., (2000) Indian Materia Medico, 1, p. 116. , Popular Prakashan Ltd., Mumbai, India; Nonfon, M., Lieb, F., Moeschler, H., Wendisch, D., Four annonins from Annona squamosa (1990) Phytochemistry, 29, pp. 1951-1954; Satyavati, G.V., Raina, M.K., Sharma, M., (1976) Medicinal Plants of India, 1, pp. 75-76. , ICMR Publication, New Delhi; Shirwaikar, A., Rajendran, K., Dinesh Kumar, C., Bodla, R.G., Antidiabetic activity of aqueous leaf extract of Annona squamosa in streptozotocin-nicotinamide type 2 diabetic rats (2004) J. Ethnopharmacol., 91, pp. 171-175; Shirwaikar, A., Rajendran, K., Dinesh Kumar, C., Oral antidiabetic activity of Annona squamosa leaf alcohol extract in NIDDM rats (2004) Pharm. Biol., 42, pp. 30-35; Sunanda, P., Anand, K., Possible amelioration of hyperthyroidism by the leaf extract of Annona squamosa (2003) Curr. Sci., 84, pp. 1402-1404; Topno, K.K., Plants used by tribals of Chotanagpur against diabetes (1997) Botanica, 47, p. 99; Trimurti, N., Alkaloids from Annona squamosa leaves (1924) J. Ind. Inst. Sci., 7, p. 232; Warrier, P.K., Nambiar, V.P.K., Raman Kutty, C., (1996) Indian Medicinal Plants, 1, p. 160. , Orient Longman, Hyderabad, India; (1992) Quality Control Methods for Medicinal Plant Materials, p. 9. , Organisation Mondiale De La Sante, Geneva; Yang, Y.L., Chang, F.R., Wu, Y.C., Total synthesis of 3,4-dihydro benzo(h) quinazolin-4-one and structure elucidation of perolidine and samoquasine A (2003) Tetra. Lett., 44, pp. 319-322; Yoganarasimhan, S., (2000) Medicinal Plants of India-Tamilnadu, 2, p. 48. , Cyber Media, Bangalore

PY - 2005

Y1 - 2005

N2 - The leaves of Annona squamosa Linn. (Annonaceae), commonly called as custard apple, are popularly used for the treatment of diabetes by various tribes in India. The leaves are also used for their powerful insecticidal activity, especially for destroying lice. This paper presents a detailed pharmacognostical study of the crude drug, folium Annona squamosa. The samples were studied using procedures of light, confocal microscopy, WHO recommended physico-chemical determinations and authentic phytochemical procedures. The physicochemical, morphological and histological parameters presented in this paper may be proposed as parameters to establish the authenticity of Annona squamosa leaf and may possibly help to differentiate the drug from its adulterants.

AB - The leaves of Annona squamosa Linn. (Annonaceae), commonly called as custard apple, are popularly used for the treatment of diabetes by various tribes in India. The leaves are also used for their powerful insecticidal activity, especially for destroying lice. This paper presents a detailed pharmacognostical study of the crude drug, folium Annona squamosa. The samples were studied using procedures of light, confocal microscopy, WHO recommended physico-chemical determinations and authentic phytochemical procedures. The physicochemical, morphological and histological parameters presented in this paper may be proposed as parameters to establish the authenticity of Annona squamosa leaf and may possibly help to differentiate the drug from its adulterants.

M3 - Article

VL - 11

SP - 213

EP - 219

JO - Natural Product Sciences

JF - Natural Product Sciences

SN - 1226-3907

IS - 4

ER -