An Outbreak of Burkholderia cepacia Bacteremia in a Neonatal Intensive Care Unit

Liz Mary Paul, Ashwini Hegde, Tanvi Pai, Subodh Shetty, Shrikala Baliga, Suchitra Shenoy

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

OBJECTIVES: To identify the source of infection, to study the clinical profile and outcomes of neonates with Burkholderia septicemia and to determine the antimicrobial susceptibility patterns of the isolates.

METHODS: The authors describe a 3 mo outbreak of nosocomial Burkholderia cepacia bacteremia involving 12 neonates. During the outbreak, ventilator humidifier water, intravenous solutions and other possible sources were taken from the concerned neonatal intensive care units (NICUs); cultured and isolates identified by standard microbiological techniques and VITEK system. Clinical details of affected babies were also obtained to ascertain the clinical significance of the isolates.

RESULTS: All neonates had clinical and biochemical evidence of sepsis and the source could be tracked to intravenous solutions of 5% dextrose, normal saline (opened bottles) and continuous positive airway pressure humidifier water. Strain relatedness of the environmental isolates with the clinical isolates is likely as antibiotic susceptibility patterns were similar.

CONCLUSIONS: The investigations revealed the source of the nosocomial outbreak which is crucial for initiating appropriate control measures.

Original languageEnglish
Pages (from-to)285-8
Number of pages4
JournalIndian Journal of Practical Pediatrics
Volume83
Issue number4
DOIs
Publication statusPublished - 04-2016

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Burkholderia cepacia
Neonatal Intensive Care Units
Bacteremia
Disease Outbreaks
Sepsis
Microbiological Techniques
Burkholderia
Continuous Positive Airway Pressure
Water
Mechanical Ventilators
Outcome Assessment (Health Care)
Anti-Bacterial Agents
Glucose
Infection
Humidifiers

Cite this

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title = "An Outbreak of Burkholderia cepacia Bacteremia in a Neonatal Intensive Care Unit",
abstract = "OBJECTIVES: To identify the source of infection, to study the clinical profile and outcomes of neonates with Burkholderia septicemia and to determine the antimicrobial susceptibility patterns of the isolates.METHODS: The authors describe a 3 mo outbreak of nosocomial Burkholderia cepacia bacteremia involving 12 neonates. During the outbreak, ventilator humidifier water, intravenous solutions and other possible sources were taken from the concerned neonatal intensive care units (NICUs); cultured and isolates identified by standard microbiological techniques and VITEK system. Clinical details of affected babies were also obtained to ascertain the clinical significance of the isolates.RESULTS: All neonates had clinical and biochemical evidence of sepsis and the source could be tracked to intravenous solutions of 5{\%} dextrose, normal saline (opened bottles) and continuous positive airway pressure humidifier water. Strain relatedness of the environmental isolates with the clinical isolates is likely as antibiotic susceptibility patterns were similar.CONCLUSIONS: The investigations revealed the source of the nosocomial outbreak which is crucial for initiating appropriate control measures.",
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An Outbreak of Burkholderia cepacia Bacteremia in a Neonatal Intensive Care Unit. / Paul, Liz Mary; Hegde, Ashwini; Pai, Tanvi; Shetty, Subodh; Baliga, Shrikala; Shenoy, Suchitra.

In: Indian Journal of Practical Pediatrics, Vol. 83, No. 4, 04.2016, p. 285-8.

Research output: Contribution to journalArticle

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T1 - An Outbreak of Burkholderia cepacia Bacteremia in a Neonatal Intensive Care Unit

AU - Paul, Liz Mary

AU - Hegde, Ashwini

AU - Pai, Tanvi

AU - Shetty, Subodh

AU - Baliga, Shrikala

AU - Shenoy, Suchitra

PY - 2016/4

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AB - OBJECTIVES: To identify the source of infection, to study the clinical profile and outcomes of neonates with Burkholderia septicemia and to determine the antimicrobial susceptibility patterns of the isolates.METHODS: The authors describe a 3 mo outbreak of nosocomial Burkholderia cepacia bacteremia involving 12 neonates. During the outbreak, ventilator humidifier water, intravenous solutions and other possible sources were taken from the concerned neonatal intensive care units (NICUs); cultured and isolates identified by standard microbiological techniques and VITEK system. Clinical details of affected babies were also obtained to ascertain the clinical significance of the isolates.RESULTS: All neonates had clinical and biochemical evidence of sepsis and the source could be tracked to intravenous solutions of 5% dextrose, normal saline (opened bottles) and continuous positive airway pressure humidifier water. Strain relatedness of the environmental isolates with the clinical isolates is likely as antibiotic susceptibility patterns were similar.CONCLUSIONS: The investigations revealed the source of the nosocomial outbreak which is crucial for initiating appropriate control measures.

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