An unusual case of intraventricular gliosarcoma

A. Govindan, D. I. Bhat, A. Mahadevan, S. Chakraborti, S. Sampath, B. A. Chandramouli, S. K. Shankar

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Gliosarcoma is an uncommon variant of glioblastoma characterized by a biphasic pattern of glial and mesenchymal differentiation in the tumor. These tumors occur mostly in the cerebral hemispheres. Intraventricular location is extremely rare. Extensive review of literature revealed only two cases of intraventricular gliosarcoma. The first case arose by malignant transformation of a preexisting ependymoma. The second case was a gliosarcoma involving the frontal lobe with extension into the lateral ventricle. We report a case of an exclusively lateral ventricular tumor probably arising from the interventricular septum and blocking the CSF pathway. To the best of our knowledge, this is the first reported case of an exclusively intraventricular gliosarcoma.

Original languageEnglish
Pages (from-to)379-383
Number of pages5
JournalClinical Neuropathology
Volume28
Issue number5
Publication statusPublished - 02-11-2009

Fingerprint

Gliosarcoma
Ependymoma
Neoplasms
Lateral Ventricles
Cerebrum
Frontal Lobe
Glioblastoma
Neuroglia

All Science Journal Classification (ASJC) codes

  • Clinical Neurology
  • Pathology and Forensic Medicine
  • Neurology

Cite this

Govindan, A., Bhat, D. I., Mahadevan, A., Chakraborti, S., Sampath, S., Chandramouli, B. A., & Shankar, S. K. (2009). An unusual case of intraventricular gliosarcoma. Clinical Neuropathology, 28(5), 379-383.
Govindan, A. ; Bhat, D. I. ; Mahadevan, A. ; Chakraborti, S. ; Sampath, S. ; Chandramouli, B. A. ; Shankar, S. K. / An unusual case of intraventricular gliosarcoma. In: Clinical Neuropathology. 2009 ; Vol. 28, No. 5. pp. 379-383.
@article{dca48e82c5fb471488c067e35bfc29d9,
title = "An unusual case of intraventricular gliosarcoma",
abstract = "Gliosarcoma is an uncommon variant of glioblastoma characterized by a biphasic pattern of glial and mesenchymal differentiation in the tumor. These tumors occur mostly in the cerebral hemispheres. Intraventricular location is extremely rare. Extensive review of literature revealed only two cases of intraventricular gliosarcoma. The first case arose by malignant transformation of a preexisting ependymoma. The second case was a gliosarcoma involving the frontal lobe with extension into the lateral ventricle. We report a case of an exclusively lateral ventricular tumor probably arising from the interventricular septum and blocking the CSF pathway. To the best of our knowledge, this is the first reported case of an exclusively intraventricular gliosarcoma.",
author = "A. Govindan and Bhat, {D. I.} and A. Mahadevan and S. Chakraborti and S. Sampath and Chandramouli, {B. A.} and Shankar, {S. K.}",
year = "2009",
month = "11",
day = "2",
language = "English",
volume = "28",
pages = "379--383",
journal = "Clinical Neuropathology",
issn = "0722-5091",
publisher = "Dustri-Verlag Dr. Karl Feistle",
number = "5",

}

Govindan, A, Bhat, DI, Mahadevan, A, Chakraborti, S, Sampath, S, Chandramouli, BA & Shankar, SK 2009, 'An unusual case of intraventricular gliosarcoma', Clinical Neuropathology, vol. 28, no. 5, pp. 379-383.

An unusual case of intraventricular gliosarcoma. / Govindan, A.; Bhat, D. I.; Mahadevan, A.; Chakraborti, S.; Sampath, S.; Chandramouli, B. A.; Shankar, S. K.

In: Clinical Neuropathology, Vol. 28, No. 5, 02.11.2009, p. 379-383.

Research output: Contribution to journalArticle

TY - JOUR

T1 - An unusual case of intraventricular gliosarcoma

AU - Govindan, A.

AU - Bhat, D. I.

AU - Mahadevan, A.

AU - Chakraborti, S.

AU - Sampath, S.

AU - Chandramouli, B. A.

AU - Shankar, S. K.

PY - 2009/11/2

Y1 - 2009/11/2

N2 - Gliosarcoma is an uncommon variant of glioblastoma characterized by a biphasic pattern of glial and mesenchymal differentiation in the tumor. These tumors occur mostly in the cerebral hemispheres. Intraventricular location is extremely rare. Extensive review of literature revealed only two cases of intraventricular gliosarcoma. The first case arose by malignant transformation of a preexisting ependymoma. The second case was a gliosarcoma involving the frontal lobe with extension into the lateral ventricle. We report a case of an exclusively lateral ventricular tumor probably arising from the interventricular septum and blocking the CSF pathway. To the best of our knowledge, this is the first reported case of an exclusively intraventricular gliosarcoma.

AB - Gliosarcoma is an uncommon variant of glioblastoma characterized by a biphasic pattern of glial and mesenchymal differentiation in the tumor. These tumors occur mostly in the cerebral hemispheres. Intraventricular location is extremely rare. Extensive review of literature revealed only two cases of intraventricular gliosarcoma. The first case arose by malignant transformation of a preexisting ependymoma. The second case was a gliosarcoma involving the frontal lobe with extension into the lateral ventricle. We report a case of an exclusively lateral ventricular tumor probably arising from the interventricular septum and blocking the CSF pathway. To the best of our knowledge, this is the first reported case of an exclusively intraventricular gliosarcoma.

UR - http://www.scopus.com/inward/record.url?scp=70350075547&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=70350075547&partnerID=8YFLogxK

M3 - Article

VL - 28

SP - 379

EP - 383

JO - Clinical Neuropathology

JF - Clinical Neuropathology

SN - 0722-5091

IS - 5

ER -

Govindan A, Bhat DI, Mahadevan A, Chakraborti S, Sampath S, Chandramouli BA et al. An unusual case of intraventricular gliosarcoma. Clinical Neuropathology. 2009 Nov 2;28(5):379-383.