An update on possible pathogenic mechanisms of periodontal pathogens on renal dysfunction

Aditi Chopra, Karthik Sivaraman

Research output: Contribution to journalReview article

1 Citation (Scopus)


Periodontitis is a potential source of permanent systemic inflammation that initiates renal dysfunction and contributes to the development of chronic kidney diseases (CKDs). Although numerous studies have confirmed the bidirectional role of periodontal infection and renal inflammation, no literature has yet highlighted the sophisticated pathogenic mechanisms by which periodontal pathogens, particularly Porphynomonas Gingivalis, induce renal dysfunction and contributed in the development of CKDs. The present review aims to critically analyze and highlight the novel pathogenesis of periodontitis induced CKDs.

Original languageEnglish
JournalCritical Reviews in Microbiology
Publication statusAccepted/In press - 01-01-2019


All Science Journal Classification (ASJC) codes

  • Microbiology
  • Applied Microbiology and Biotechnology

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