Anti inflammatory and free radical scavenging studies of Hyptis suaveolens (Labiatae)

R. Shenoy, A. Shirwaikar

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

The ethanolic extract of H. suaveolens was tested to study the effects on the inflammatory reaction, using the technique of Carageenan induced paw edema in albino rats. The extract showed significant anti inflammatory activity comparable to the reference standard Ibuprofen. Antioxidant investigations of the ethanol extract along with its fraction using nitric oxide induced free radical assay methods showed good free radical scavenging activity thereby supporting its anti-inflammatory properties.
Original languageEnglish
Pages (from-to)574-577
Number of pages4
JournalIndian Drugs
Volume39
Issue number11
Publication statusPublished - 2002

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Hyptis
Lamiaceae
Free Radicals
Anti-Inflammatory Agents
Ibuprofen
Edema
Nitric Oxide
Ethanol
Antioxidants

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Shenoy, R. ; Shirwaikar, A. / Anti inflammatory and free radical scavenging studies of Hyptis suaveolens (Labiatae). In: Indian Drugs. 2002 ; Vol. 39, No. 11. pp. 574-577.
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abstract = "The ethanolic extract of H. suaveolens was tested to study the effects on the inflammatory reaction, using the technique of Carageenan induced paw edema in albino rats. The extract showed significant anti inflammatory activity comparable to the reference standard Ibuprofen. Antioxidant investigations of the ethanol extract along with its fraction using nitric oxide induced free radical assay methods showed good free radical scavenging activity thereby supporting its anti-inflammatory properties.",
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note = "Cited By :8 Export Date: 10 November 2017 CODEN: INDRB Correspondence Address: Shirwaikar, A.; Department of Pharmacognosy, College of Pharmaceutical Sciences, M.A.H.E., Manipal 576119, Karnataka, India Chemicals/CAS: alcohol, 64-17-5; gum arabic, 9000-01-5; ibuprofen, 15687-27-1; nitric oxide, 10102-43-9 References: (1964) The Wealth of India, Raw Materials, 5, p. 123. , (C.S.I.R., New Delhi); Chopra, R.N., Naya, S.L., Chopra, I.C., (1986) Glossary of Indian Medicinal Plants, p. 45. , (C.S.I.R., New Delhi); Kirtikar, K.R., Basu, B.D., (1991) Indian Medicinal Plants, 3, p. 2032; Conner, E.M., Grisham, M.B., Inflammation, free radicals and antioxidants (1996) Nutrition, 12, p. 274; Harborne, J.B., (1998) Phytochemical Methods, pp. 60-66. , Chapman and Hall, London; Kokate, C.K., (1991) Practical Pharmacognosy, 10-13, pp. 107-121. , Vallabh Prakashan, Delhi; Winter, C.A., Risley, G.A., Nuss, G.W., (1962) Proc. Soc. Exp. Bio. Med, 111, pp. 544-547; Sreejayan, Rao, M.N.A., Nitric oxide scavenging by Curcuminoids (1997) J. Pharm. Pharmacol., 49, p. 105; Hemnani, T., Parihar, M.S., Reactive oxygen species and oxidative DNA damage (1998) Indian J Physiol Pharmacol, 42, p. 440; Marrieta, M.A., Nitric oxide: Biosynthesis and biological significance (1989) Trends Biol Sci, 14, p. 488; Havsteen, B., Flavonoids, a class of natural products of high pharmacological potency (1983) Biochem. Pharmacol, 32, pp. 1141-1148",
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Shenoy, R & Shirwaikar, A 2002, 'Anti inflammatory and free radical scavenging studies of Hyptis suaveolens (Labiatae)', Indian Drugs, vol. 39, no. 11, pp. 574-577.

Anti inflammatory and free radical scavenging studies of Hyptis suaveolens (Labiatae). / Shenoy, R.; Shirwaikar, A.

In: Indian Drugs, Vol. 39, No. 11, 2002, p. 574-577.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Anti inflammatory and free radical scavenging studies of Hyptis suaveolens (Labiatae)

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AU - Shirwaikar, A.

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PY - 2002

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N2 - The ethanolic extract of H. suaveolens was tested to study the effects on the inflammatory reaction, using the technique of Carageenan induced paw edema in albino rats. The extract showed significant anti inflammatory activity comparable to the reference standard Ibuprofen. Antioxidant investigations of the ethanol extract along with its fraction using nitric oxide induced free radical assay methods showed good free radical scavenging activity thereby supporting its anti-inflammatory properties.

AB - The ethanolic extract of H. suaveolens was tested to study the effects on the inflammatory reaction, using the technique of Carageenan induced paw edema in albino rats. The extract showed significant anti inflammatory activity comparable to the reference standard Ibuprofen. Antioxidant investigations of the ethanol extract along with its fraction using nitric oxide induced free radical assay methods showed good free radical scavenging activity thereby supporting its anti-inflammatory properties.

M3 - Article

VL - 39

SP - 574

EP - 577

JO - Indian Drugs

JF - Indian Drugs

SN - 0019-462X

IS - 11

ER -