Anti-snake venom activity of different extracts of Pouzolzia indica against Russel viper venom

A. Ahmed, K. Rajendaran, D. Jaiswal, H.P. Singh, A. Mishra, D. Chandra, I.K. Yadav, D.A. Jain

Research output: Contribution to journalArticlepeer-review

17 Citations (Scopus)

Abstract

Snakebite is an important cause of morbidity and mortality and is one of the major health problems in India. Russell's viper or daboia (Viper russelli) appears to be the commonest cause of fatal snakebite in Southern India, Pakistan, Bangladesh, Sri Lanka, Burma and Thailand. Intravenous administration of antibothropic antivenom neutralizes the systemic actions, but it is of little effect on the reversal of local symptoms and often induces adverse reactions, a context that drives the search for complementary treatments for snakebite accidents. Vegetable extracts with a range of antiophidian activities constitute an excellent alternative. In this study, we investigated the anti-venom effects of different extracts of Pouzolzia indica. The alcoholic and aqueous extracts of P. indica showed potent snake venom neutralizing capacity against Russell viper venom.
Original languageEnglish
Pages (from-to)744-751
Number of pages8
JournalInternational Journal of ChemTech Research
Volume2
Issue number1
Publication statusPublished - 2010

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