A few novel 2,5-disubstituted-1,3,4-oxadiazole derivatives were synthesized and evaluated for antitubercular activity. The anti-tubercular activity was carried out as per the Rist and Grosset proportion method. Among the eight derivatives, the compounds substituted at ortho-position of the aromatic ring showed anti-tubercular activity comparable with the standard, isoniazid.
|Number of pages||5|
|Publication status||Published - 2015|
Durgashivaprasad, E., Attari, Z., Mudgal, J., Bairy, L. K., Vishnu Prasad, S., & Kutty Nampurath, G. (2015). Anti-tubercular activity of synthesized novel 2, 5-disubstituted-1, 3, 4-oxadiazole derivatives. Indian Drugs, 52(2), 40-44..