Anti-tubercular activity of synthesized novel 2, 5-disubstituted-1, 3, 4-oxadiazole derivatives

Ega Durgashivaprasad, Zenab Attari, Jayesh Mudgal, Laxminaryana Kurady Bairy, S Vishnu Prasad, Gopalan Kutty Nampurath

Research output: Contribution to journalArticle

Abstract

A few novel 2,5-disubstituted-1,3,4-oxadiazole derivatives were synthesized and evaluated for antitubercular activity. The anti-tubercular activity was carried out as per the Rist and Grosset proportion method. Among the eight derivatives, the compounds substituted at ortho-position of the aromatic ring showed anti-tubercular activity comparable with the standard, isoniazid.
Original languageEnglish
Pages (from-to) 40-44.
Number of pages5
JournalIndian Drugs
Volume52
Issue number2
Publication statusPublished - 2015

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Isoniazid
1,3,4-oxadiazole

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Durgashivaprasad, E., Attari, Z., Mudgal, J., Bairy, L. K., Vishnu Prasad, S., & Kutty Nampurath, G. (2015). Anti-tubercular activity of synthesized novel 2, 5-disubstituted-1, 3, 4-oxadiazole derivatives. Indian Drugs, 52(2), 40-44..
Durgashivaprasad, Ega ; Attari, Zenab ; Mudgal, Jayesh ; Bairy, Laxminaryana Kurady ; Vishnu Prasad, S ; Kutty Nampurath, Gopalan. / Anti-tubercular activity of synthesized novel 2, 5-disubstituted-1, 3, 4-oxadiazole derivatives. In: Indian Drugs. 2015 ; Vol. 52, No. 2. pp. 40-44.
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abstract = "A few novel 2,5-disubstituted-1,3,4-oxadiazole derivatives were synthesized and evaluated for antitubercular activity. The anti-tubercular activity was carried out as per the Rist and Grosset proportion method. Among the eight derivatives, the compounds substituted at ortho-position of the aromatic ring showed anti-tubercular activity comparable with the standard, isoniazid.",
author = "Ega Durgashivaprasad and Zenab Attari and Jayesh Mudgal and Bairy, {Laxminaryana Kurady} and {Vishnu Prasad}, S and {Kutty Nampurath}, Gopalan",
year = "2015",
language = "English",
volume = "52",
pages = "40--44.",
journal = "Indian Drugs",
issn = "0019-462X",
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Durgashivaprasad, E, Attari, Z, Mudgal, J, Bairy, LK, Vishnu Prasad, S & Kutty Nampurath, G 2015, 'Anti-tubercular activity of synthesized novel 2, 5-disubstituted-1, 3, 4-oxadiazole derivatives', Indian Drugs, vol. 52, no. 2, pp. 40-44..

Anti-tubercular activity of synthesized novel 2, 5-disubstituted-1, 3, 4-oxadiazole derivatives. / Durgashivaprasad, Ega; Attari, Zenab; Mudgal, Jayesh; Bairy, Laxminaryana Kurady; Vishnu Prasad, S; Kutty Nampurath, Gopalan.

In: Indian Drugs, Vol. 52, No. 2, 2015, p. 40-44.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Anti-tubercular activity of synthesized novel 2, 5-disubstituted-1, 3, 4-oxadiazole derivatives

AU - Durgashivaprasad, Ega

AU - Attari, Zenab

AU - Mudgal, Jayesh

AU - Bairy, Laxminaryana Kurady

AU - Vishnu Prasad, S

AU - Kutty Nampurath, Gopalan

PY - 2015

Y1 - 2015

N2 - A few novel 2,5-disubstituted-1,3,4-oxadiazole derivatives were synthesized and evaluated for antitubercular activity. The anti-tubercular activity was carried out as per the Rist and Grosset proportion method. Among the eight derivatives, the compounds substituted at ortho-position of the aromatic ring showed anti-tubercular activity comparable with the standard, isoniazid.

AB - A few novel 2,5-disubstituted-1,3,4-oxadiazole derivatives were synthesized and evaluated for antitubercular activity. The anti-tubercular activity was carried out as per the Rist and Grosset proportion method. Among the eight derivatives, the compounds substituted at ortho-position of the aromatic ring showed anti-tubercular activity comparable with the standard, isoniazid.

M3 - Article

VL - 52

SP - 40-44.

JO - Indian Drugs

JF - Indian Drugs

SN - 0019-462X

IS - 2

ER -