Anti-tubercular activity of synthesized novel 2, 5-disubstituted-1, 3, 4-oxadiazole derivatives

Ega Durgashivaprasad, Zenab Attari, Jayesh Mudgal, Laxminaryana Kurady Bairy, S Vishnu Prasad, Gopalan Kutty Nampurath

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)

Abstract

A few novel 2,5-disubstituted-1,3,4-oxadiazole derivatives were synthesized and evaluated for antitubercular activity. The anti-tubercular activity was carried out as per the Rist and Grosset proportion method. Among the eight derivatives, the compounds substituted at ortho-position of the aromatic ring showed anti-tubercular activity comparable with the standard, isoniazid.
Original languageEnglish
Pages (from-to) 40-44.
Number of pages5
JournalIndian Drugs
Volume52
Issue number2
Publication statusPublished - 2015

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