Anticonvulsant activity of enzyme inhibitors in rats

K. Ramabadran, M. Bansinath, M.N. Guruswami

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)


Three liver microsomal enzyme inhibitors, proadifen, 2,4‐dichloro‐6‐phenylphenoxyethyldiethylamine, and 2,4‐dichloro‐6‐phenylphenoxyethylamine, and a hepatotoxic agent, carbon tetrachloride, were tested for anticonvulsant activity in adult male albino rats using the maximal electroshock seizure technique. All four substances exhibited significant anticonvulsant activity 1 hr after intraperitoneal administration. This protection was absent when tested 24 hr later. Copyright © 1976 Wiley‐Liss, Inc., A Wiley Company
Original languageEnglish
Pages (from-to)1245-1246
Number of pages2
JournalJournal of Pharmaceutical Sciences
Issue number8
Publication statusPublished - 1976
Externally publishedYes


Dive into the research topics of 'Anticonvulsant activity of enzyme inhibitors in rats'. Together they form a unique fingerprint.

Cite this