Abstract

This research work is carried out to assess the antimicrobial efficacy of an antiplaque agent, Hybnex® against the leading periodontal pathogens which are known to cause periodontal disease. Complete exclusion of these infective microbes and thereby impeding disease progression is the prime focus of periodontal therapy, which is virtually achieved by scaling and root planing. However, for maintenance of such perceptible conditions are carried out by the adjunctive use of antimicrobial agents. A total of fifteen intact human single rooted teeth were inoculated with periodontal pathogens to form a biofilm. The biofilm formed was confirmed using scanning electron microscope (SEM). The specimens were then divided into 3 groups. Group I: specimens were treated with test agent. Group II: specimens were treated with 0.2% Chlorhexidine (CHX) AND Group III: Specimens were treated with deionized water. The results showed comparable antimicrobial activity between test agent (Hybnex®) and CHX (0.2%) when compared to the deionized water, which was statistically significant (p < 0.001).

Original languageEnglish
Pages (from-to)89-90
Number of pages2
JournalInternational Journal of Clinical Dentistry
Volume11
Issue number2
Publication statusPublished - 01-01-2018

Fingerprint

Chlorhexidine
Biofilms
Root Planing
Water
Periodontal Diseases
Anti-Infective Agents
Disease Progression
Tooth
Maintenance
Electrons
Research
Therapeutics

All Science Journal Classification (ASJC) codes

  • Dentistry(all)

Cite this

@article{16452044f5c54334a34f2906ccf24343,
title = "Antimicrobial efficacy of a denovo anti-plaque agent against periodontal pathogens",
abstract = "This research work is carried out to assess the antimicrobial efficacy of an antiplaque agent, Hybnex{\circledR} against the leading periodontal pathogens which are known to cause periodontal disease. Complete exclusion of these infective microbes and thereby impeding disease progression is the prime focus of periodontal therapy, which is virtually achieved by scaling and root planing. However, for maintenance of such perceptible conditions are carried out by the adjunctive use of antimicrobial agents. A total of fifteen intact human single rooted teeth were inoculated with periodontal pathogens to form a biofilm. The biofilm formed was confirmed using scanning electron microscope (SEM). The specimens were then divided into 3 groups. Group I: specimens were treated with test agent. Group II: specimens were treated with 0.2{\%} Chlorhexidine (CHX) AND Group III: Specimens were treated with deionized water. The results showed comparable antimicrobial activity between test agent (Hybnex{\circledR}) and CHX (0.2{\%}) when compared to the deionized water, which was statistically significant (p < 0.001).",
author = "Jothi Varghese and Vasudev Ballal",
year = "2018",
month = "1",
day = "1",
language = "English",
volume = "11",
pages = "89--90",
journal = "International Journal of Clinical Dentistry",
issn = "1939-5833",
publisher = "Nova Science Publishers Inc",
number = "2",

}

TY - JOUR

T1 - Antimicrobial efficacy of a denovo anti-plaque agent against periodontal pathogens

AU - Varghese, Jothi

AU - Ballal, Vasudev

PY - 2018/1/1

Y1 - 2018/1/1

N2 - This research work is carried out to assess the antimicrobial efficacy of an antiplaque agent, Hybnex® against the leading periodontal pathogens which are known to cause periodontal disease. Complete exclusion of these infective microbes and thereby impeding disease progression is the prime focus of periodontal therapy, which is virtually achieved by scaling and root planing. However, for maintenance of such perceptible conditions are carried out by the adjunctive use of antimicrobial agents. A total of fifteen intact human single rooted teeth were inoculated with periodontal pathogens to form a biofilm. The biofilm formed was confirmed using scanning electron microscope (SEM). The specimens were then divided into 3 groups. Group I: specimens were treated with test agent. Group II: specimens were treated with 0.2% Chlorhexidine (CHX) AND Group III: Specimens were treated with deionized water. The results showed comparable antimicrobial activity between test agent (Hybnex®) and CHX (0.2%) when compared to the deionized water, which was statistically significant (p < 0.001).

AB - This research work is carried out to assess the antimicrobial efficacy of an antiplaque agent, Hybnex® against the leading periodontal pathogens which are known to cause periodontal disease. Complete exclusion of these infective microbes and thereby impeding disease progression is the prime focus of periodontal therapy, which is virtually achieved by scaling and root planing. However, for maintenance of such perceptible conditions are carried out by the adjunctive use of antimicrobial agents. A total of fifteen intact human single rooted teeth were inoculated with periodontal pathogens to form a biofilm. The biofilm formed was confirmed using scanning electron microscope (SEM). The specimens were then divided into 3 groups. Group I: specimens were treated with test agent. Group II: specimens were treated with 0.2% Chlorhexidine (CHX) AND Group III: Specimens were treated with deionized water. The results showed comparable antimicrobial activity between test agent (Hybnex®) and CHX (0.2%) when compared to the deionized water, which was statistically significant (p < 0.001).

UR - http://www.scopus.com/inward/record.url?scp=85056103665&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85056103665&partnerID=8YFLogxK

M3 - Article

VL - 11

SP - 89

EP - 90

JO - International Journal of Clinical Dentistry

JF - International Journal of Clinical Dentistry

SN - 1939-5833

IS - 2

ER -