Antioxidant and antihepatotoxic activities of Hemidesmus indicus R. Br

G. M.Mohana Rao, Ch Venkateswararao, A. K.S. Rawat, P. Pushpangadan, A. Shirwaikar

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Abstract

The Antioxidant and antihepatotoxic activities of 50% aqueous ethanolic extract of Hemidesmus indicus R. Br. roots were assessed in experimental animals. In carbontetrachloride induced hepatic challenge in rats, a remarkable elevation of lipid peroxidation and a decrease in liver antioxidant enzymes levels were observed. Pretreatment with the 50% aqueous ethanol extract of Hemidesmus indicus R. Br. roots inhibited these alterations. Based on these results we can suggest that in the liver protective and antioxidative effects of H. indicus, possibly involve mechanisms related to free radical scavenging effects.

Original languageEnglish
Pages (from-to)107-113
Number of pages7
JournalActa Pharmaceutica Turcica
Volume47
Issue number2
Publication statusPublished - 2005
Externally publishedYes

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All Science Journal Classification (ASJC) codes

  • Pharmaceutical Science

Cite this

Rao, G. M. M., Venkateswararao, C., Rawat, A. K. S., Pushpangadan, P., & Shirwaikar, A. (2005). Antioxidant and antihepatotoxic activities of Hemidesmus indicus R. Br. Acta Pharmaceutica Turcica, 47(2), 107-113.