Antioxidant and antihepatotoxic activities of Hemidesmus indicus R. Br

G. M. Mohana Rao, Ch Venkateswararao, A. K.S. Rawat, P. Pushpangadan, A. Shirwaikar

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

The Antioxidant and antihepatotoxic activities of 50% aqueous ethanolic extract of Hemidesmus indicus R. Br. roots were assessed in experimental animals. In carbontetrachloride induced hepatic challenge in rats, a remarkable elevation of lipid peroxidation and a decrease in liver antioxidant enzymes levels were observed. Pretreatment with the 50% aqueous ethanol extract of Hemidesmus indicus R. Br. roots inhibited these alterations. Based on these results we can suggest that in the liver protective and antioxidative effects of H. Indicus, possibly involve mechanisms related to free radical scavenging effects.

Original languageEnglish
Pages (from-to)73-78
Number of pages6
JournalActa Pharmaceutica Turcica
Volume47
Issue number1
Publication statusPublished - 2005
Externally publishedYes

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Hemidesmus
Antioxidants
Liver
Lipid Peroxidation
Free Radicals
Ethanol
Enzymes

All Science Journal Classification (ASJC) codes

  • Pharmaceutical Science

Cite this

Mohana Rao, G. M., Venkateswararao, C., Rawat, A. K. S., Pushpangadan, P., & Shirwaikar, A. (2005). Antioxidant and antihepatotoxic activities of Hemidesmus indicus R. Br. Acta Pharmaceutica Turcica, 47(1), 73-78.
Mohana Rao, G. M. ; Venkateswararao, Ch ; Rawat, A. K.S. ; Pushpangadan, P. ; Shirwaikar, A. / Antioxidant and antihepatotoxic activities of Hemidesmus indicus R. Br. In: Acta Pharmaceutica Turcica. 2005 ; Vol. 47, No. 1. pp. 73-78.
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Mohana Rao, GM, Venkateswararao, C, Rawat, AKS, Pushpangadan, P & Shirwaikar, A 2005, 'Antioxidant and antihepatotoxic activities of Hemidesmus indicus R. Br', Acta Pharmaceutica Turcica, vol. 47, no. 1, pp. 73-78.

Antioxidant and antihepatotoxic activities of Hemidesmus indicus R. Br. / Mohana Rao, G. M.; Venkateswararao, Ch; Rawat, A. K.S.; Pushpangadan, P.; Shirwaikar, A.

In: Acta Pharmaceutica Turcica, Vol. 47, No. 1, 2005, p. 73-78.

Research output: Contribution to journalArticle

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Mohana Rao GM, Venkateswararao C, Rawat AKS, Pushpangadan P, Shirwaikar A. Antioxidant and antihepatotoxic activities of Hemidesmus indicus R. Br. Acta Pharmaceutica Turcica. 2005;47(1):73-78.