Antioxidant [In vitro] and analgesic activity [In vivo] of tannin fraction of stem bark of Ficus racemosa Linn

Sankaradoss Nirmala, S. Arun, Naveen Bathula, M. Sivanagamoorthi, Velayudem Ravichandiran

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1 Citation (Scopus)

Abstract

The purpose of the present study was to investigate the antioxidant and analgesic effect of the tannin fraction of stem bark of Ficus racemosa Linn. The antioxidant potential of tannin fraction was tested in DPPH, FRAP assay in vitro model and the analgesic activity was done by using Eddys hot plate method. In antioxidant assays the tannin fraction shows the very good free radical scavenging capacity and In eddy's hot plate method the tannin fraction showed significant analgesic activity at the doses of 20 mg/kg [p<0.01] and 40 mg/kg [p<0.001] and 60 mg/kg [p<0.001] as compared to control group, when analyzed statistically by Dunnet's multiple comparison Test. The result obtained show that the tannin fraction of Ficus racemosa Linn. Possesses significant antioxidant potential & analgesic activity which confirms the traditional claims of the plant mentioned in Ayurveda.

Original languageEnglish
Pages (from-to)597-603
Number of pages7
JournalResearch Journal of Pharmaceutical, Biological and Chemical Sciences
Volume3
Issue number1
Publication statusPublished - 01-01-2012
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Biochemistry, Genetics and Molecular Biology(all)
  • Pharmacology, Toxicology and Pharmaceutics(all)

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