Antioxidant studies on the methanol stem extract of Coscinium fenestration

A. Shirwaikar, I.S.R. Punitha

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25 Citations (Scopus)

Abstract

The methanol extract of Coscinium fenestratum, commonly known as tree turmeric, which is widely used in the indigenous system of medicine was studied for its in vitro scavenging activity in different methods viz DPPH scavenging, nitric oxide scavenging, iron chelation activity, superoxide scavenging, ABTS radical scavenging and lipid peroxidation. The results were analyzed statistically by regression method. Its antioxidant activity was estimated by IC50 value and the values are 57.1 μg/ml for DPPH radical scavenging, 36.5 μg/ml for iron chelating activity, 51.7 μg/ml for nitric oxide scavenging, 53.63 μg/ml for ABTS scavenging, 44.2 μg/ml for superoxide scavenging, and 40 μg/ml for lipid peroxidation. In all the methods, the extract showed its ability to scavenge free radicals in a concentration dependent manner. The results indicate that C. fenestratum has potent antioxidant activity.
Original languageEnglish
Pages (from-to)40-45
Number of pages6
JournalNatural Product Sciences
Volume13
Issue number1
Publication statusPublished - 2007
Externally publishedYes

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