Application of spectroscopic techniques for the analysis of kidney stones: A pilot study

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Identification and characterization of kidney stone remains one of the important analytical tasks in the medical field. Kidney stone is a common health complication throughout the world, which may cause severe pain, obstruction and infection of urinary tract, and can lead to complete renal damage. It commonly occurs in both sexes regardless of age. Kidney stones have different composition, although each stones have a major single characteristic component. A complete understanding of a sample properties and their function can only be feasible by utilizing elemental and molecular information simultaneously. Two laser based analytical techniques; Laser Induced Breakdown spectroscopy (LIBS) and Raman spectroscopy have been used to study different types of kidney stones from different patients. LIBS and Raman spectroscopy are highly complementary spectroscopic techniques, which provide elemental and molecular information of a sample. Q-switched Nd:YAG laser at 355 nm laser having energy 17mJ per pulse at 10 Hz repetition rate was used for getting LIBS spectra. Raman measurements were carried out using a home assembled micro-Raman spectrometer. Using the recorded Raman spectra of kidney stones, we were able to differentiate different kinds of kidney stones. LIBS spectra of the same stones are showing the evidence of C, Ca, H, and O and also suggest the presence of certain pigments.

Original languageEnglish
Title of host publicationOptical Diagnostics and Sensing XVI
Subtitle of host publicationToward Point-of-Care Diagnostics
PublisherSPIE
Volume9715
ISBN (Electronic)9781628419498
DOIs
Publication statusPublished - 01-01-2016
EventOptical Diagnostics and Sensing XVI: Toward Point-of-Care Diagnostics - San Francisco, United States
Duration: 15-02-201616-02-2016

Conference

ConferenceOptical Diagnostics and Sensing XVI: Toward Point-of-Care Diagnostics
CountryUnited States
CitySan Francisco
Period15-02-1616-02-16

    Fingerprint

All Science Journal Classification (ASJC) codes

  • Atomic and Molecular Physics, and Optics
  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Radiology Nuclear Medicine and imaging

Cite this

Shameem, K. M. M., Chawla, A., Bankapur, A., Unnikrishnan, V. K., & Santhosh, C. (2016). Application of spectroscopic techniques for the analysis of kidney stones: A pilot study. In Optical Diagnostics and Sensing XVI: Toward Point-of-Care Diagnostics (Vol. 9715). [97151E] SPIE. https://doi.org/10.1117/12.2214865