Assessment of serum calcium and phosphorus in pulmonary tuberculosis patients before, during and after chemotherapy

K. Rohini, Surekha Bhat, P. S. Srikumar, A. Mahesh Kumar

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Our study was aimed to assess the levels of serum calcium and phosphorus in pulmonary tuberculosis patients. Blood samples were collected from 40 patients with pulmonary tuberculosis before treatment (PTB-0), at the end of 2 months of intensive phase of treatment (PTB-2) and after 6 months of treatment (PTB-6). Age and weight matched normal healthy volunteers (n = 37) served as normal controls. Serum was analyzed for calcium and phosphorus. Serum calcium significantly decreased to hypocalcemic levels and serum phosphorus significantly decreased but was within normophosphatemic limits in pulmonary tuberculosis. Chemotherapy for tuberculosis managed to raise serum levels of both the ions, with hypocalcemia still persisting in majority of patients during treatment but getting resolved in a significant percentage of patients at the end of 6 months of treatment. Results indicate the need for calcium and phosphorus supplements in tuberculosis patients during chemotherapy. This study also warrants the need for regular monitoring of serum calcium and phosphorus in patients undergoing anti-tuberculosis treatment.

Original languageEnglish
Pages (from-to)377-381
Number of pages5
JournalIndian Journal of Clinical Biochemistry
Volume29
Issue number3
DOIs
Publication statusPublished - 01-01-2014
Externally publishedYes

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Chemotherapy
Pulmonary Tuberculosis
Phosphorus
Calcium
Drug Therapy
Serum
Tuberculosis
Patient treatment
Healthy Volunteers
Therapeutics
Hypocalcemia
Blood
Ions
Monitoring
Weights and Measures

All Science Journal Classification (ASJC) codes

  • Clinical Biochemistry

Cite this

Rohini, K. ; Bhat, Surekha ; Srikumar, P. S. ; Mahesh Kumar, A. / Assessment of serum calcium and phosphorus in pulmonary tuberculosis patients before, during and after chemotherapy. In: Indian Journal of Clinical Biochemistry. 2014 ; Vol. 29, No. 3. pp. 377-381.
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Assessment of serum calcium and phosphorus in pulmonary tuberculosis patients before, during and after chemotherapy. / Rohini, K.; Bhat, Surekha; Srikumar, P. S.; Mahesh Kumar, A.

In: Indian Journal of Clinical Biochemistry, Vol. 29, No. 3, 01.01.2014, p. 377-381.

Research output: Contribution to journalArticle

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