Assets and liabilities of drug repositioning

Research output: Contribution to journalArticle

Abstract

Drug discovery is an awfully tenacious job that takes an enormous amount of time, resources, and money, yet yields unsubstantial results. Drug repositioning is a method for "discovering new uses for old drugs." The main objective to repurpose a drug is to extend the application line of an existing drug, thereby narrowing the productivity gap and at the same time allows a swift reach to the market with high chances of revenues. This approach aims at new formulations, dosage, drug combination, delivery system, alternative pathways and targets, orphan diseases. Likewise the de novo drug development, drug repositioning also shares many pros and cons. At one hand, drug repositioning offers relatively less riskversus- reward ratio; on the other hand, the regulatory authority approval process, intellectual property rights and out-licensing are issues of concern. This review article will particularly focus on the various pros and cons associated with drug repositioning.

Original languageEnglish
Pages (from-to)P47-P53
JournalInternational Journal of Pharma and Bio Sciences
Volume7
Issue number4
Publication statusPublished - 01-01-2016

Fingerprint

Drug Repositioning
Pharmaceutical Preparations
Intellectual Property
Ownership
Drug Combinations
Drug Discovery
Licensure
Drug Delivery Systems
Rare Diseases
Reward
Hand
Intellectual property
Efficiency
Productivity

All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Biochemistry
  • Molecular Biology
  • Cell Biology

Cite this

@article{b4ea35dbf5f24ee6a3b783483eb30934,
title = "Assets and liabilities of drug repositioning",
abstract = "Drug discovery is an awfully tenacious job that takes an enormous amount of time, resources, and money, yet yields unsubstantial results. Drug repositioning is a method for {"}discovering new uses for old drugs.{"} The main objective to repurpose a drug is to extend the application line of an existing drug, thereby narrowing the productivity gap and at the same time allows a swift reach to the market with high chances of revenues. This approach aims at new formulations, dosage, drug combination, delivery system, alternative pathways and targets, orphan diseases. Likewise the de novo drug development, drug repositioning also shares many pros and cons. At one hand, drug repositioning offers relatively less riskversus- reward ratio; on the other hand, the regulatory authority approval process, intellectual property rights and out-licensing are issues of concern. This review article will particularly focus on the various pros and cons associated with drug repositioning.",
author = "Rupam Gill and {Amberkar Mohan Babu}, V. and {Meena Kumari}, K.",
year = "2016",
month = "1",
day = "1",
language = "English",
volume = "7",
pages = "P47--P53",
journal = "International Journal of Pharma and Bio Sciences",
issn = "0975-6299",
publisher = "International Journal of Pharma and Bio Sciences",
number = "4",

}

Assets and liabilities of drug repositioning. / Gill, Rupam; Amberkar Mohan Babu, V.; Meena Kumari, K.

In: International Journal of Pharma and Bio Sciences, Vol. 7, No. 4, 01.01.2016, p. P47-P53.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Assets and liabilities of drug repositioning

AU - Gill, Rupam

AU - Amberkar Mohan Babu, V.

AU - Meena Kumari, K.

PY - 2016/1/1

Y1 - 2016/1/1

N2 - Drug discovery is an awfully tenacious job that takes an enormous amount of time, resources, and money, yet yields unsubstantial results. Drug repositioning is a method for "discovering new uses for old drugs." The main objective to repurpose a drug is to extend the application line of an existing drug, thereby narrowing the productivity gap and at the same time allows a swift reach to the market with high chances of revenues. This approach aims at new formulations, dosage, drug combination, delivery system, alternative pathways and targets, orphan diseases. Likewise the de novo drug development, drug repositioning also shares many pros and cons. At one hand, drug repositioning offers relatively less riskversus- reward ratio; on the other hand, the regulatory authority approval process, intellectual property rights and out-licensing are issues of concern. This review article will particularly focus on the various pros and cons associated with drug repositioning.

AB - Drug discovery is an awfully tenacious job that takes an enormous amount of time, resources, and money, yet yields unsubstantial results. Drug repositioning is a method for "discovering new uses for old drugs." The main objective to repurpose a drug is to extend the application line of an existing drug, thereby narrowing the productivity gap and at the same time allows a swift reach to the market with high chances of revenues. This approach aims at new formulations, dosage, drug combination, delivery system, alternative pathways and targets, orphan diseases. Likewise the de novo drug development, drug repositioning also shares many pros and cons. At one hand, drug repositioning offers relatively less riskversus- reward ratio; on the other hand, the regulatory authority approval process, intellectual property rights and out-licensing are issues of concern. This review article will particularly focus on the various pros and cons associated with drug repositioning.

UR - http://www.scopus.com/inward/record.url?scp=84992187053&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84992187053&partnerID=8YFLogxK

M3 - Article

VL - 7

SP - P47-P53

JO - International Journal of Pharma and Bio Sciences

JF - International Journal of Pharma and Bio Sciences

SN - 0975-6299

IS - 4

ER -