Assisted ventilation in neonates

The Manipal experience

Lalitha Krishnan, Paul Prabhakar Francis, Nirupa A. D'Souza, Nalini Bhaskaranand

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Case records of 68 newborns who required assisted ventilation over a 24 month period were reviewed. Fortyfour (64.7%) received intermittent mandatory ventilation, 10 (14.7%) received nasal CPAP and the remaining 14 (20.58%) received a combination of the above. Some of the indications for ventilation were infections (21), hyaline membrane disease (16), problems related to asphyxia (11), apnea of prematurity (10) and persistent pulmonary hypertension of newborn (5). The overall survival rate was 41.17%. In the CPAP group 90% (9/10) survived, while in the remaining survival was 32.7% (19/58). The best outcome was observed in persistent pulmonary hypertension of newborn (80%) followed by apnea of prematurity (70%) and hyaline membrane disease (43.75). Outcome was poor in conditions related to birth asphyxia (27.2%) and infections (19.05%). Survival rates were higher (44.4%) in babies weighing >1500g at birth as compared to 40.9% in babies <1500g. Babies less than 32 weeks gestation had a survival rate of 32% as compared to 46.5% in those over 32 weeks. This difference was not statistically significant. Complications were seen in 12/68 patients (17.6%). Pneumothorax was the commonest followed by sepsis, intrventricular hemorrhage and blocked endotracheal tubes. Babies with hyaline membrane disease had the highest incidence of complications. Analysis of the data with regard to the indications, outcome and complications is presented.

Original languageEnglish
Pages (from-to)379-386
Number of pages8
JournalThe Indian Journal of Pediatrics
Volume61
Issue number4
DOIs
Publication statusPublished - 01-07-1994
Externally publishedYes

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Hyaline Membrane Disease
Persistent Fetal Circulation Syndrome
Ventilation
Survival Rate
Asphyxia
Newborn Infant
Apnea
Parturition
Pneumothorax
Infection
Nose
Sepsis
Hemorrhage
Pregnancy
Survival
Incidence

All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health

Cite this

Krishnan, L., Francis, P. P., D'Souza, N. A., & Bhaskaranand, N. (1994). Assisted ventilation in neonates: The Manipal experience. The Indian Journal of Pediatrics, 61(4), 379-386. https://doi.org/10.1007/BF02751895
Krishnan, Lalitha ; Francis, Paul Prabhakar ; D'Souza, Nirupa A. ; Bhaskaranand, Nalini. / Assisted ventilation in neonates : The Manipal experience. In: The Indian Journal of Pediatrics. 1994 ; Vol. 61, No. 4. pp. 379-386.
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Krishnan, L, Francis, PP, D'Souza, NA & Bhaskaranand, N 1994, 'Assisted ventilation in neonates: The Manipal experience', The Indian Journal of Pediatrics, vol. 61, no. 4, pp. 379-386. https://doi.org/10.1007/BF02751895

Assisted ventilation in neonates : The Manipal experience. / Krishnan, Lalitha; Francis, Paul Prabhakar; D'Souza, Nirupa A.; Bhaskaranand, Nalini.

In: The Indian Journal of Pediatrics, Vol. 61, No. 4, 01.07.1994, p. 379-386.

Research output: Contribution to journalArticle

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Krishnan L, Francis PP, D'Souza NA, Bhaskaranand N. Assisted ventilation in neonates: The Manipal experience. The Indian Journal of Pediatrics. 1994 Jul 1;61(4):379-386. https://doi.org/10.1007/BF02751895