Association between immunological status and caries experience among adults attending Hospital Universiti Sains Malaysia (HUSM)

Wan Majdiah Wan Mohamad, Wan Nor Aini Bt Wan Aziz, Noorliza Mastura Ismail, Rehana Basri, Mohammad Khursheed Alam

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Background: Dental caries is one of the most prevalent chronic diseases affecting people worldwide. It is one of the most common bacterial infections in humans. Studies have shown that the immunological response of dental caries in children and adults vary. The immunological status of patients with dental caries may help in long term management of the problem. Objectives: This study aims to evaluate the levels of serum immunoglobulin G, A and M among adults and to determine its association with caries experience. Materials and Methods: Thirty healthy adults aged 18-60 years old attending the HUSM Dental Clinic were randomly selected. There were 9 males and 21 females. Oral examination was done to determine caries experience using the DMFT index. Blood samples were taken and serum immunoglobulin levels (IgG, A and M) were analyzed using nephelometer. The study was approved by Universiti Sains Malaysia Human Ethics Committee. Results: Majority of them were Malays (86.7%) and 13.3% were Chinese. They were grouped according to low (DMFT = 0), moderate (DMFT = 1-4) and high (DMFT > 4) caries experience. Serum immunoglobulin G, A and M levels was found to be normal in all groups. There was no significant association between serum immunoglobulin levels and caries experience. Conclusion: Although caries experience varies widely, the serum immunoglobulin levels were within the normal range.

Original languageEnglish
Pages (from-to)208-210
Number of pages3
JournalInternational Medical Journal
Volume20
Issue number2
Publication statusPublished - 01-04-2013
Externally publishedYes

Fingerprint

Malaysia
Dental Caries
Immunoglobulins
Serum
Immunoglobulin G
Immunoglobulin M
Dental Clinics
Oral Diagnosis
Ethics Committees
Bacterial Infections
Reference Values
Chronic Disease

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

Wan Mohamad, W. M., Wan Aziz, W. N. A. B., Ismail, N. M., Basri, R., & Alam, M. K. (2013). Association between immunological status and caries experience among adults attending Hospital Universiti Sains Malaysia (HUSM). International Medical Journal, 20(2), 208-210.
Wan Mohamad, Wan Majdiah ; Wan Aziz, Wan Nor Aini Bt ; Ismail, Noorliza Mastura ; Basri, Rehana ; Alam, Mohammad Khursheed. / Association between immunological status and caries experience among adults attending Hospital Universiti Sains Malaysia (HUSM). In: International Medical Journal. 2013 ; Vol. 20, No. 2. pp. 208-210.
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abstract = "Background: Dental caries is one of the most prevalent chronic diseases affecting people worldwide. It is one of the most common bacterial infections in humans. Studies have shown that the immunological response of dental caries in children and adults vary. The immunological status of patients with dental caries may help in long term management of the problem. Objectives: This study aims to evaluate the levels of serum immunoglobulin G, A and M among adults and to determine its association with caries experience. Materials and Methods: Thirty healthy adults aged 18-60 years old attending the HUSM Dental Clinic were randomly selected. There were 9 males and 21 females. Oral examination was done to determine caries experience using the DMFT index. Blood samples were taken and serum immunoglobulin levels (IgG, A and M) were analyzed using nephelometer. The study was approved by Universiti Sains Malaysia Human Ethics Committee. Results: Majority of them were Malays (86.7{\%}) and 13.3{\%} were Chinese. They were grouped according to low (DMFT = 0), moderate (DMFT = 1-4) and high (DMFT > 4) caries experience. Serum immunoglobulin G, A and M levels was found to be normal in all groups. There was no significant association between serum immunoglobulin levels and caries experience. Conclusion: Although caries experience varies widely, the serum immunoglobulin levels were within the normal range.",
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Wan Mohamad, WM, Wan Aziz, WNAB, Ismail, NM, Basri, R & Alam, MK 2013, 'Association between immunological status and caries experience among adults attending Hospital Universiti Sains Malaysia (HUSM)', International Medical Journal, vol. 20, no. 2, pp. 208-210.

Association between immunological status and caries experience among adults attending Hospital Universiti Sains Malaysia (HUSM). / Wan Mohamad, Wan Majdiah; Wan Aziz, Wan Nor Aini Bt; Ismail, Noorliza Mastura; Basri, Rehana; Alam, Mohammad Khursheed.

In: International Medical Journal, Vol. 20, No. 2, 01.04.2013, p. 208-210.

Research output: Contribution to journalArticle

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