Association of postprandial blood sugar with hypercoagulability in comparison to fasting blood sugars in diabetic and healthy patients

A cross-sectional study

Sri Ramulu Kadiyala, Karthik Rao, N. R. Rao, Ram Bhat, Jayaprakash Rao, P. Navin, O. Balaji

Research output: Contribution to journalArticle

Abstract

Objective: The aim of this study was to find the association of postprandial blood glucose with hypercoagulability in comparison to fasting blood sugars(FBS) in diabetic and healthy patients. Methods: The present study involved a total of 156 patients, of which 78 were taken as cases (diabetics) and other 78 as controls (non-diabetics). Laboratory analysis included prothrombin time (PT), activated partial thromboplastin time (APTT), fibrinogen assay done along with fasting, and postprandial sugars. Results: Platelets in diabetics and healthy controls were in normal range. Decrease in PT and partial thromboplastin time was noted in diabetics compared to non-diabetic controls. Fibrinogen levels were increased in cases compared to controls. Changes in PT values were more significant with postprandial blood sugar (PPBS) levels when compared to FBS levels, and APTT follows the same pattern with more in PPBS levels and FBS levels in diabetics. PPBS showed elevated fibrinogen when compared to FBS in diabetics as well as non-diabetics. Conclusion: Type 2 diabetes mellitus is a hypercoagulable state as proven by the following results of our study.

Original languageEnglish
Pages (from-to)378-384
Number of pages7
JournalAsian Journal of Pharmaceutical and Clinical Research
Volume10
Issue number7
DOIs
Publication statusPublished - 01-01-2017
Externally publishedYes

Fingerprint

Thrombophilia
Blood Glucose
Fasting
Cross-Sectional Studies
Partial Thromboplastin Time
Prothrombin Time
Fibrinogen
Type 2 Diabetes Mellitus
Reference Values
Blood Platelets

All Science Journal Classification (ASJC) codes

  • Pharmacology
  • Pharmaceutical Science
  • Pharmacology (medical)

Cite this

@article{b5d320eb371847b5b2681017d1c54a9f,
title = "Association of postprandial blood sugar with hypercoagulability in comparison to fasting blood sugars in diabetic and healthy patients: A cross-sectional study",
abstract = "Objective: The aim of this study was to find the association of postprandial blood glucose with hypercoagulability in comparison to fasting blood sugars(FBS) in diabetic and healthy patients. Methods: The present study involved a total of 156 patients, of which 78 were taken as cases (diabetics) and other 78 as controls (non-diabetics). Laboratory analysis included prothrombin time (PT), activated partial thromboplastin time (APTT), fibrinogen assay done along with fasting, and postprandial sugars. Results: Platelets in diabetics and healthy controls were in normal range. Decrease in PT and partial thromboplastin time was noted in diabetics compared to non-diabetic controls. Fibrinogen levels were increased in cases compared to controls. Changes in PT values were more significant with postprandial blood sugar (PPBS) levels when compared to FBS levels, and APTT follows the same pattern with more in PPBS levels and FBS levels in diabetics. PPBS showed elevated fibrinogen when compared to FBS in diabetics as well as non-diabetics. Conclusion: Type 2 diabetes mellitus is a hypercoagulable state as proven by the following results of our study.",
author = "Kadiyala, {Sri Ramulu} and Karthik Rao and Rao, {N. R.} and Ram Bhat and Jayaprakash Rao and P. Navin and O. Balaji",
year = "2017",
month = "1",
day = "1",
doi = "10.22159/ajpcr.2017.v10i7.18806",
language = "English",
volume = "10",
pages = "378--384",
journal = "Asian Journal of Pharmaceutical and Clinical Research",
issn = "0974-2441",
publisher = "Innovare Academics Sciences Pvt. Ltd",
number = "7",

}

Association of postprandial blood sugar with hypercoagulability in comparison to fasting blood sugars in diabetic and healthy patients : A cross-sectional study. / Kadiyala, Sri Ramulu; Rao, Karthik; Rao, N. R.; Bhat, Ram; Rao, Jayaprakash; Navin, P.; Balaji, O.

In: Asian Journal of Pharmaceutical and Clinical Research, Vol. 10, No. 7, 01.01.2017, p. 378-384.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Association of postprandial blood sugar with hypercoagulability in comparison to fasting blood sugars in diabetic and healthy patients

T2 - A cross-sectional study

AU - Kadiyala, Sri Ramulu

AU - Rao, Karthik

AU - Rao, N. R.

AU - Bhat, Ram

AU - Rao, Jayaprakash

AU - Navin, P.

AU - Balaji, O.

PY - 2017/1/1

Y1 - 2017/1/1

N2 - Objective: The aim of this study was to find the association of postprandial blood glucose with hypercoagulability in comparison to fasting blood sugars(FBS) in diabetic and healthy patients. Methods: The present study involved a total of 156 patients, of which 78 were taken as cases (diabetics) and other 78 as controls (non-diabetics). Laboratory analysis included prothrombin time (PT), activated partial thromboplastin time (APTT), fibrinogen assay done along with fasting, and postprandial sugars. Results: Platelets in diabetics and healthy controls were in normal range. Decrease in PT and partial thromboplastin time was noted in diabetics compared to non-diabetic controls. Fibrinogen levels were increased in cases compared to controls. Changes in PT values were more significant with postprandial blood sugar (PPBS) levels when compared to FBS levels, and APTT follows the same pattern with more in PPBS levels and FBS levels in diabetics. PPBS showed elevated fibrinogen when compared to FBS in diabetics as well as non-diabetics. Conclusion: Type 2 diabetes mellitus is a hypercoagulable state as proven by the following results of our study.

AB - Objective: The aim of this study was to find the association of postprandial blood glucose with hypercoagulability in comparison to fasting blood sugars(FBS) in diabetic and healthy patients. Methods: The present study involved a total of 156 patients, of which 78 were taken as cases (diabetics) and other 78 as controls (non-diabetics). Laboratory analysis included prothrombin time (PT), activated partial thromboplastin time (APTT), fibrinogen assay done along with fasting, and postprandial sugars. Results: Platelets in diabetics and healthy controls were in normal range. Decrease in PT and partial thromboplastin time was noted in diabetics compared to non-diabetic controls. Fibrinogen levels were increased in cases compared to controls. Changes in PT values were more significant with postprandial blood sugar (PPBS) levels when compared to FBS levels, and APTT follows the same pattern with more in PPBS levels and FBS levels in diabetics. PPBS showed elevated fibrinogen when compared to FBS in diabetics as well as non-diabetics. Conclusion: Type 2 diabetes mellitus is a hypercoagulable state as proven by the following results of our study.

UR - http://www.scopus.com/inward/record.url?scp=85021724388&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85021724388&partnerID=8YFLogxK

U2 - 10.22159/ajpcr.2017.v10i7.18806

DO - 10.22159/ajpcr.2017.v10i7.18806

M3 - Article

VL - 10

SP - 378

EP - 384

JO - Asian Journal of Pharmaceutical and Clinical Research

JF - Asian Journal of Pharmaceutical and Clinical Research

SN - 0974-2441

IS - 7

ER -