Auditory P300 event-related potential: Normative data in the Indian population

N. Uvais, S. Nizamie, Basudeb Das, Samir Praharaj, Mohammad Ul Haq Katshu

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Objective: To generate the normative data of auditory P300 event-related potential for various age groups in the Indian population. Materials and Methods: Auditory P300 event-related potentials, using the oddball paradigm, of healthy control participants in studies carried out at our institute were included to generate normative data in the age range of 10-50 years. The amplitude and latency of P300 for Fz, Cz, and Pz were selected for analysis. Results: For P300 amplitude, overall multivariate analysis of variance (MANOVA) was significant [Pillai's Trace F (9/453) = 3.46, P < 0.001]. Follow-up ANOVA showed significant difference across age groups at Fz, Cz, and Pz. For P300 latency, there was a trend towards significance for overall MANOVA [Pillai's Trace F (9/453) = 1.68, P = 0.09]. Follow-up ANOVA showed a trend towards significant difference across age groups at Fz only. Conclusion: Our study generated a P300 amplitude and frequency normative database at Fz, Cz, and Pz, which will serve as a reference for future studies attempting to define P300 abnormalities in various psychiatric disorders in Indian population.

Original languageEnglish
Pages (from-to)176-180
Number of pages5
JournalNeurology India
Volume66
Issue number1
DOIs
Publication statusPublished - 01-01-2018

All Science Journal Classification (ASJC) codes

  • Neurology
  • Clinical Neurology

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