Automated diagnosis of depression electroencephalograph signals using linear prediction coding and higher order spectra features

G. Muralidhar Bairy, Oh Shu Lih, Yuki Hagiwara, Subha D. Puthankattil, Oliver Faust, U. C. Niranjan, U. Rajendra Acharya

Research output: Contribution to journalArticle

9 Citations (Scopus)


Depression is a mental disorder that negatively affects the day to day activities of a patient. Diagnosing depression is of paramount importance to reduce suffering for the patient and support network. Electroencephalograph (EEG) signal variations can indicate neurological diseases associated with mental trauma. EEG being a non-invasive technique, is widely used to analyse various brain disorders. However, to detect and interpret the minute signal changes a computer-aided diagnosis (CAD) system is developed. Higher order statistic based parameters, such as variance, kurtosis, normalized kurtosis, skewness, normalized skewness is extracted from the linear predictive coding (LPC) residuals. Seven different feature ranking methods are used to test and rank the extracted features. Feature ranking using Receiver Operating Characteristic (ROC) gave the best classification accuracy of 94.30%, the sensitivity of 91.46% and specificity of 97.45% using a bag tree classifier.

Original languageEnglish
Pages (from-to)1857-1862
Number of pages6
JournalJournal of Medical Imaging and Health Informatics
Issue number8
Publication statusPublished - 01-12-2017


All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging
  • Health Informatics

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