Rahul Sharma, Pradip Sircar, R. B. Pachori, Sulatha V. Bhandary, U. Rajendra Acharya

Research output: Contribution to journalArticlepeer-review

9 Citations (Scopus)


Glaucoma is one of the leading causes of blindness. The raised intraocular pressure is one of the important modifiable risk factor causing glaucomatous optic nerve damage. Glaucomatous optic nerve damage is seen as increase in the cupping of the optic disc and loss of neuroretinal rim. An automated detection system using nonlinear higher order statistics (HOS) based method is used to capture the detailed information present in the fundus image efficiently. The center slice of bispectrum and bicepstrum are applied on fundus images. Various features are extracted from the diagonal of these central slices. In order to reduce the number of features the locality sensitive discriminant analysis (LSDA) data reduction technique method is implemented. The ranked LSDA features are fed to support vector machine (SVM) classifier with various kernels for automated glaucoma detection. The simulation is performed on two databases. The proposed algorithm has yielded classification accuracy of 98.8% and 95% using entire private and public databases, respectively. The proposed technique achieved the highest classification accuracy, hence, confirm the diagnosis of ophthalmologists and can be employed in the community health care centers and hospitals.

Original languageEnglish
Article number1940011
JournalJournal of Mechanics in Medicine and Biology
Issue number1
Publication statusPublished - 01-02-2019

All Science Journal Classification (ASJC) codes

  • Biomedical Engineering

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