Bacteriological profile of catheter associated urinary tract infection and its antimicrobial susceptibility pattern in a tertiary care hospital

M. S. Nandini, Kiran Madhusudan

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2 Citations (Scopus)

Abstract

Among nosocomial infections catheter associated urinary infection (CAUTI) is one of the most common infection. Uropathogens isolated from CAUTI were more multi-drug resistant than from community acquired urinary tract infection (UTI). Hence the aim of this study is to isolate uro-pathogens from CAUTI and find out anti microbial sensitivity pattern among the isolates. Materials and methods: A prospective study was conducted from July 2015 to Jan 2016, urine samples were collected from 250 patients with CAUTI which were processed microbiologically and antimicrobial sensitivity was performed. Results: Out of 250, 54 patients developed CAUTI and Escherichia coli (34.61%) was the most common organism followed by Klebsiella (21.15%), Pseudomonas (17.30%), Proteus (7.69%) and Acinetobacter (9.61%). Among the Gram positive isolates Staphylococcus aureus and Enterococcus was isolated and MRSA strains were 66.67%. Enterobacteriaceae showed high resistant to commonly used antimicrobials Gentamycin, Ceftriaxone, Ofloxacin, ciprofloxacin and were highly sensitive to Amikacin, ceftazidime, pipercillin tazobactum, imepenem, Meropenem. ESBL producers among Gram negative bacilli were 11(23.40%). Conclusion: 34(62.96%) Patients developed CAUTI on 7th day of catheterization and many isolates showed multi-drug resistance pattern, hence strict aseptic precaution has to be taken prior to catheter insertion and care after to prevent infection.

Original languageEnglish
Pages (from-to)204-207
Number of pages4
JournalJournal of Pharmaceutical Sciences and Research
Volume8
Issue number4
Publication statusPublished - 01-04-2016

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Catheter-Related Infections
Tertiary Healthcare
Tertiary Care Centers
Urinary Tract Infections
meropenem
Community-Acquired Infections
Proteus
Piperacillin
Acinetobacter
Ofloxacin
Ceftazidime
Klebsiella
Amikacin
Ceftriaxone
Enterococcus
Multiple Drug Resistance
Enterobacteriaceae
Methicillin-Resistant Staphylococcus aureus
Ciprofloxacin
Cross Infection

All Science Journal Classification (ASJC) codes

  • Pharmaceutical Science

Cite this

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title = "Bacteriological profile of catheter associated urinary tract infection and its antimicrobial susceptibility pattern in a tertiary care hospital",
abstract = "Among nosocomial infections catheter associated urinary infection (CAUTI) is one of the most common infection. Uropathogens isolated from CAUTI were more multi-drug resistant than from community acquired urinary tract infection (UTI). Hence the aim of this study is to isolate uro-pathogens from CAUTI and find out anti microbial sensitivity pattern among the isolates. Materials and methods: A prospective study was conducted from July 2015 to Jan 2016, urine samples were collected from 250 patients with CAUTI which were processed microbiologically and antimicrobial sensitivity was performed. Results: Out of 250, 54 patients developed CAUTI and Escherichia coli (34.61{\%}) was the most common organism followed by Klebsiella (21.15{\%}), Pseudomonas (17.30{\%}), Proteus (7.69{\%}) and Acinetobacter (9.61{\%}). Among the Gram positive isolates Staphylococcus aureus and Enterococcus was isolated and MRSA strains were 66.67{\%}. Enterobacteriaceae showed high resistant to commonly used antimicrobials Gentamycin, Ceftriaxone, Ofloxacin, ciprofloxacin and were highly sensitive to Amikacin, ceftazidime, pipercillin tazobactum, imepenem, Meropenem. ESBL producers among Gram negative bacilli were 11(23.40{\%}). Conclusion: 34(62.96{\%}) Patients developed CAUTI on 7th day of catheterization and many isolates showed multi-drug resistance pattern, hence strict aseptic precaution has to be taken prior to catheter insertion and care after to prevent infection.",
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AU - Madhusudan, Kiran

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N2 - Among nosocomial infections catheter associated urinary infection (CAUTI) is one of the most common infection. Uropathogens isolated from CAUTI were more multi-drug resistant than from community acquired urinary tract infection (UTI). Hence the aim of this study is to isolate uro-pathogens from CAUTI and find out anti microbial sensitivity pattern among the isolates. Materials and methods: A prospective study was conducted from July 2015 to Jan 2016, urine samples were collected from 250 patients with CAUTI which were processed microbiologically and antimicrobial sensitivity was performed. Results: Out of 250, 54 patients developed CAUTI and Escherichia coli (34.61%) was the most common organism followed by Klebsiella (21.15%), Pseudomonas (17.30%), Proteus (7.69%) and Acinetobacter (9.61%). Among the Gram positive isolates Staphylococcus aureus and Enterococcus was isolated and MRSA strains were 66.67%. Enterobacteriaceae showed high resistant to commonly used antimicrobials Gentamycin, Ceftriaxone, Ofloxacin, ciprofloxacin and were highly sensitive to Amikacin, ceftazidime, pipercillin tazobactum, imepenem, Meropenem. ESBL producers among Gram negative bacilli were 11(23.40%). Conclusion: 34(62.96%) Patients developed CAUTI on 7th day of catheterization and many isolates showed multi-drug resistance pattern, hence strict aseptic precaution has to be taken prior to catheter insertion and care after to prevent infection.

AB - Among nosocomial infections catheter associated urinary infection (CAUTI) is one of the most common infection. Uropathogens isolated from CAUTI were more multi-drug resistant than from community acquired urinary tract infection (UTI). Hence the aim of this study is to isolate uro-pathogens from CAUTI and find out anti microbial sensitivity pattern among the isolates. Materials and methods: A prospective study was conducted from July 2015 to Jan 2016, urine samples were collected from 250 patients with CAUTI which were processed microbiologically and antimicrobial sensitivity was performed. Results: Out of 250, 54 patients developed CAUTI and Escherichia coli (34.61%) was the most common organism followed by Klebsiella (21.15%), Pseudomonas (17.30%), Proteus (7.69%) and Acinetobacter (9.61%). Among the Gram positive isolates Staphylococcus aureus and Enterococcus was isolated and MRSA strains were 66.67%. Enterobacteriaceae showed high resistant to commonly used antimicrobials Gentamycin, Ceftriaxone, Ofloxacin, ciprofloxacin and were highly sensitive to Amikacin, ceftazidime, pipercillin tazobactum, imepenem, Meropenem. ESBL producers among Gram negative bacilli were 11(23.40%). Conclusion: 34(62.96%) Patients developed CAUTI on 7th day of catheterization and many isolates showed multi-drug resistance pattern, hence strict aseptic precaution has to be taken prior to catheter insertion and care after to prevent infection.

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