Bipolar affective disorder associated with thenar hypoplasia: Is lithium safe?

Samir Kumar Praharaj, Aleem Siddiqui, Vinod Kumar Sinha

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Thenar hypoplasia has been described to occur as a part of radial longitudinal deficiency syndromes and occasionally related to Holt-Oram syndrome in which both cardiac and skeletal abnormalities co-occur. We describe a case with bilateral thenar hypoplasia, which resembles a milder variety of Holt-Oram syndrome, who developed bradycardia after exposure to lithium at therapeutic doses.

Original languageEnglish
JournalAmerican Journal of Therapeutics
Issue number4
Publication statusPublished - 01-07-2010


All Science Journal Classification (ASJC) codes

  • Pharmacology
  • Pharmacology (medical)

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