Cerebral malaria in a man with Plasmodium vivax mono-infection: a case report

Himanshu Gupta, Pushwinder Dhunputh, Ankita N. Bhatt, Kapaettu Satyamoorthy, Shashikiran Umakanth

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Cerebral malaria (CM) is a diffuse encephalopathy associated with coma and seizures commonly caused by Plasmodium falciparum (P. falciparum) in children with severe malaria. We present a case of a 19-year-old man with CM due to Plasmodium vivax (P. vivax) infection. Cerebrospinal fluid (CSF) was negative for Japanese B encephalitis, enterovirus, herpes simplex 1 and 2, varicella and mumps viruses as determined by real-time polymerase chain reaction (PCR). P. falciparum and P. vivax species were analysed by microscopy, immunochromatography and PCR assays and confirmed mono-infection of P. vivax in the patient’s blood, and P. falciparum infection was established to be negative. The patient was discharged after intensive supportive care and antimalarial treatment (intravenous artesunate and oral doxycycline). We conclude that P. vivax infection is associated with CM, a life-threatening complication rarely seen in coastal districts of Karnataka. In endemic areas, the possibility of CM should be considered even with P. vivax infection.

Original languageEnglish
Pages (from-to)241-245
Number of pages5
JournalTropical Doctor
Volume46
Issue number4
DOIs
Publication statusPublished - 01-10-2016

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Cerebral Malaria
Plasmodium vivax
Malaria
Plasmodium falciparum
Infection
Immunochromatography
Mumps virus
Japanese Encephalitis
Herpes Simplex
Chickenpox
Enterovirus
Doxycycline
Antimalarials
Brain Diseases
Critical Care
Coma
Cerebrospinal Fluid
Real-Time Polymerase Chain Reaction
Microscopy
Seizures

All Science Journal Classification (ASJC) codes

  • Public Health, Environmental and Occupational Health
  • Infectious Diseases

Cite this

Gupta, Himanshu ; Dhunputh, Pushwinder ; Bhatt, Ankita N. ; Satyamoorthy, Kapaettu ; Umakanth, Shashikiran. / Cerebral malaria in a man with Plasmodium vivax mono-infection : a case report. In: Tropical Doctor. 2016 ; Vol. 46, No. 4. pp. 241-245.
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Cerebral malaria in a man with Plasmodium vivax mono-infection : a case report. / Gupta, Himanshu; Dhunputh, Pushwinder; Bhatt, Ankita N.; Satyamoorthy, Kapaettu; Umakanth, Shashikiran.

In: Tropical Doctor, Vol. 46, No. 4, 01.10.2016, p. 241-245.

Research output: Contribution to journalArticle

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