Characteristics and correlates of poststroke depression: An Indian study

Amlan Kusum Jana, Suddhendu Chakraborty, Samir Kumar Praharaj

Research output: Contribution to journalArticle

Abstract

Background: Post stroke depression adversely affects long term outcome of stroke and increases mortality risk. Few studies have looked into the comprehensive picture of post stroke depression in past. Aim: The current study aimed to look into the phenomenology, characteristic features and various correlates of post stroke depression. Method: 142 consecutive stroke patients aged 60 years or above, fulfilling the inclusion criteria were assessed. Sociodemographic and clinical data were gathered using a specially designed pro-forma. Depression, apathy and psychosis were assessed by Post stroke depression rating scale, Apathy Evaluation Scale, and Brief Psychiatric Rating Scale respectively. Groups (with or without major depression) were compared using Mann-Whitney U, chi square or Fisher's exact test. One way ANOVA was conducted to see the relations of lesion location and laterality with various clinical parameters. Kaplan-Meier survival analysis was done to see the time to develop depression. The effect sizes were reported as r and partial eta squared. Results: Guilt was significantly higher (p<.05) with lesions in parietal lobe and remaining of middle cerebral artery territory. Catastrophic reaction (p<.05) and emotional dyscontrol (p<.05) were higher for diffuse lesions, periventricular lesions and lesions in frontal/occipital lobe. BPRS score, but not apathy, had a significant positive correlation with depression (Pearson's r=.692). Mean time to develop depression after stroke was 28.34 (95% CI 22.37 to 34.31) months. Conclusions: Post stroke depression consists of various clinically important sub-components whose occurrence varies with different lesion locations. Post stroke depression is discriminable from apathy but is related to psychosis.

Original languageEnglish
Pages (from-to)605-611
Number of pages7
JournalIndian Journal of Psychiatry
Volume61
Issue number6
DOIs
Publication statusPublished - 01-11-2019

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Depression
Stroke
Apathy
Psychotic Disorders
Brief Psychiatric Rating Scale
Occipital Lobe
Parietal Lobe
Guilt
Middle Cerebral Artery
Kaplan-Meier Estimate
Frontal Lobe
Survival Analysis
Analysis of Variance
Mortality

All Science Journal Classification (ASJC) codes

  • Psychiatry and Mental health

Cite this

Jana, Amlan Kusum ; Chakraborty, Suddhendu ; Praharaj, Samir Kumar. / Characteristics and correlates of poststroke depression : An Indian study. In: Indian Journal of Psychiatry. 2019 ; Vol. 61, No. 6. pp. 605-611.
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Characteristics and correlates of poststroke depression : An Indian study. / Jana, Amlan Kusum; Chakraborty, Suddhendu; Praharaj, Samir Kumar.

In: Indian Journal of Psychiatry, Vol. 61, No. 6, 01.11.2019, p. 605-611.

Research output: Contribution to journalArticle

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