Fifteen components of the essential Oil of L. conferta were identified by GC-MS analysis. The main components were identified to be a-phcllandrene (52.2% and thymol (38.2% The antifungal activity at 1:50 dilution in ethylene glycol was found to be of the same order as that of griseofulvin (1001Jg/ 0.1 ml). The oil also possessed good anthelmintic activity. The crude alcoholic extract after the removal of the oil showed significant reduction in the epithelisation period compared to that of controls in excision wound models. Nevadensin isolated from the plant showed good anti-inflammatory activity in an acute inflammation model, and exhibited moderate cytotoxic activity and anti-tubercular activity. L. heterophylla on chemical analysis afforded hymenoxin.
All Science Journal Classification (ASJC) codes
- Molecular Medicine
- Pharmaceutical Science
- Drug Discovery
- Complementary and alternative medicine