The antihepatotoxic activity of different fractions of the ethanolic extract of Lagenaria siceraria fruit, administered orally to different groups of rats was evaluated using the CCl4-induced hepatotoxicity test. All fractions tested, in a dose of 250 mg/kg showed significant activity, with the petroleum ether traction exhibiting comparatively higher activity. Two steroids were isolated from the petroleum ether fraction and they were identified as fucosterol and campesterol.
|Number of pages||6|
|Journal||Indian Journal of Pharmaceutical Sciences|
|Publication status||Published - 1996|
Shirwaikar, A., & Sreenivasan, K. K. (1996). Chemical investigation and antihepatotoxic activity of the fruits of Lagenaria siceraria. Indian Journal of Pharmaceutical Sciences, 58(5), 197-202. https://www.scopus.com/inward/record.uri?eid=2-s2.0-0029844979&partnerID=40&md5=1ec30ae215ff069384af9ef61f747553