Chemical standardization of mega sanjeevi maathirai, a herbometallic siddha drug

R. Sathish, R. Murugesan, Arul Amuthan

Research output: Contribution to journalArticle

Abstract

Siddha system of medicine believes herbometallic formulation to be potent than herbal formulation alone. So far, fewer studies have been conducted on standardization of such preparations. Mega sanjeevi mathirai (MSM), a traditional Siddha herbometallic drug was prepared as per the procedures mentioned in a siddha literature. The chemical finger print was taken by using modern analytical techniques like Inductive coupled plasma optical emission spectroscopy (ICP-OES) and Fourier transform infra-red spectroscopy (FTIR). In addition, the particle size of mega sanjeevi mathirai was also assessed by High Resolution Scanning Electron Microscope (HR SEM). The results confirmed the absence of lead, arsenic and cadmium. Reports showed the presence of inorganic elements such as mercury (2.96ppm), sodium (6.26ppm), potassium (4.22ppm), calcium (15.10ppm), phosphorous (3.63ppm) and sulphur (6.25ppm). FTIR confirmed the presence of organic moieties as follows; IR (KBr, cm -1), 3399 (-OH structure of -COOH group), 1716 (C=O structure of carboxylic acid), 1618 (C=N structure), 1214 (Asymmetric C-O-C structure), 1047 (Symmetric C-O-C structure). The range of particle size varies between 3-10 μ. These findings could be used as a chemical fingerprint for future reference of Mega sanjeevi mathirai in chemical standardization.

Original languageEnglish
Pages (from-to)35-38
Number of pages4
JournalInternational Journal of Pharmaceutical Sciences Review and Research
Volume13
Issue number2
Publication statusPublished - 01-03-2012

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Spectrum Analysis
Fourier Analysis
Particle Size
Ayurvedic Medicine
Pharmaceutical Preparations
Dermatoglyphics
Arsenic
Carboxylic Acids
Systems Analysis
Mercury
Cadmium
Sulfur
Fingers
Potassium
Sodium
Electrons
Calcium
Lead
potassium bromide

All Science Journal Classification (ASJC) codes

  • Pharmaceutical Science

Cite this

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abstract = "Siddha system of medicine believes herbometallic formulation to be potent than herbal formulation alone. So far, fewer studies have been conducted on standardization of such preparations. Mega sanjeevi mathirai (MSM), a traditional Siddha herbometallic drug was prepared as per the procedures mentioned in a siddha literature. The chemical finger print was taken by using modern analytical techniques like Inductive coupled plasma optical emission spectroscopy (ICP-OES) and Fourier transform infra-red spectroscopy (FTIR). In addition, the particle size of mega sanjeevi mathirai was also assessed by High Resolution Scanning Electron Microscope (HR SEM). The results confirmed the absence of lead, arsenic and cadmium. Reports showed the presence of inorganic elements such as mercury (2.96ppm), sodium (6.26ppm), potassium (4.22ppm), calcium (15.10ppm), phosphorous (3.63ppm) and sulphur (6.25ppm). FTIR confirmed the presence of organic moieties as follows; IR (KBr, cm -1), 3399 (-OH structure of -COOH group), 1716 (C=O structure of carboxylic acid), 1618 (C=N structure), 1214 (Asymmetric C-O-C structure), 1047 (Symmetric C-O-C structure). The range of particle size varies between 3-10 μ. These findings could be used as a chemical fingerprint for future reference of Mega sanjeevi mathirai in chemical standardization.",
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Chemical standardization of mega sanjeevi maathirai, a herbometallic siddha drug. / Sathish, R.; Murugesan, R.; Amuthan, Arul.

In: International Journal of Pharmaceutical Sciences Review and Research, Vol. 13, No. 2, 01.03.2012, p. 35-38.

Research output: Contribution to journalArticle

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