Abstract

Nephrotic Syndrome (NS), a unique renal disease complex associated with heavy proteinuria (protein excretion >3.5 gm/day), hypoalbuminemia (<30 gm/L) and peripheral oedema is a rare entity in pregnancy with an incidence of about 0.012-0.025%. There have been very few reports of pregnancy with co-existing NS. We hereby report a case of steroid sensitive childhood onset NS, due to minimal change disease and her course through two pregnancies. While she had a relapse of NS during her first pregnancy, she sailed through her second pregnancy without relapse. Women with NS can have a good maternal and perinatal outcome with multidisciplinary approach, and pregnancy does not always worsen the existing NS by causing a relapse or disease progression.

Original languageEnglish
Pages (from-to)QD08-QD09
JournalJournal of Clinical and Diagnostic Research
Volume12
Issue number7
DOIs
Publication statusPublished - 01-07-2018

Fingerprint

Nephrotic Syndrome
Pregnancy
Recurrence
Steroids
Lipoid Nephrosis
Hypoalbuminemia
Proteinuria
Disease Progression
Edema
Proteins
Mothers
Kidney
Incidence

All Science Journal Classification (ASJC) codes

  • Clinical Biochemistry

Cite this

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title = "Childhood onset nephrotic syndrome-a journey through two pregnancies",
abstract = "Nephrotic Syndrome (NS), a unique renal disease complex associated with heavy proteinuria (protein excretion >3.5 gm/day), hypoalbuminemia (<30 gm/L) and peripheral oedema is a rare entity in pregnancy with an incidence of about 0.012-0.025{\%}. There have been very few reports of pregnancy with co-existing NS. We hereby report a case of steroid sensitive childhood onset NS, due to minimal change disease and her course through two pregnancies. While she had a relapse of NS during her first pregnancy, she sailed through her second pregnancy without relapse. Women with NS can have a good maternal and perinatal outcome with multidisciplinary approach, and pregnancy does not always worsen the existing NS by causing a relapse or disease progression.",
author = "Bhat, {Shashikala K.} and Shashikiran Umakanth and Krupa Shah and Ashwini, {A. P.} and Ravindra Prabhu",
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