Chronotherapeutics and disease management: Treatment in synchrony with body's rhythms - An emerging science

K.B. Aithal, N.M. Harish, M. Rathnanand, A. Shirwaikar

Research output: Contribution to journalArticle

1 Citation (Scopus)
Original languageEnglish
Pages (from-to)15-18
Number of pages4
JournalPharma Times
Volume38
Issue number10
Publication statusPublished - 2006

Cite this

@article{addd60a980ff4f668cb35355484153ee,
title = "Chronotherapeutics and disease management: Treatment in synchrony with body's rhythms - An emerging science",
author = "K.B. Aithal and N.M. Harish and M. Rathnanand and A. Shirwaikar",
note = "Cited By :1 Export Date: 10 November 2017 Correspondence Address: Shirwaikar, A.; Dept. of Pharmaceutics, Manipal College of Pharmaceutical Sciences, Manipal, India; email: arunshirwaikar@yahoo.co.in References: Jha, N., Bapat, S., (2004) Chronobiology and chronotherapeutics, 2, pp. 384-388. , Kathmandu Univ Med J; Levi, F., From circadian rhythms to cancer chronotherapeutics (2002) Chronobiol Int, 19, pp. 1-19; Micheal, H., The brain, circadian rhythms and clock genes (1998) Br Med J, 317, pp. 1704-1708; Isadora, S., A time to heal: Chronotherapy tunes in to body's rhythms (1997) FDA Consumer, 31, pp. 16-20; Sarasija, S., Stutie, P., Chronotherapeutics: Emerging role of biorhythms in optimizing drug therapy (2005) Indian J Pharm Sci, 67, pp. 135-140; Lemmer, B., Chronopharmacology: Time, a key in drug treatment (1994) Ann Biol Clin, 52, pp. 1-7; Reinberg, A.E., Concepts of circadian chronopharmacology (1991) Ann N Y Acad Sci, 618, pp. 102-115; Willich, S.N., Levy, D., Rocco, M.B., Circadian variation in the incidence of sudden cardiac death in the Framingham Heart Study population (1987) Am J Cardiol, 60, pp. 801-806; Pickering, T.G., James, G.D., Determinants and consequences of the diurnal rhythm of blood pressure (1993) Am J Hypertens, 6, pp. 166S-169S; White, W.B., Circadian variation in blood pressure (1997) Blood Press Monit, 2, pp. 46-51; Millar-Craig, M.W., Bishop, C.N., Raftery, E.B., Circadian variation of blood pressure (1978) Lancet, 1, pp. 795-797; Anwar, Y.A., White, W.B., Chronotherapeutics for cardiovascular disease (1998) Drugs, 55, pp. 631-643; Yusuf, S., Sleight, P., Pogue, J., Effects of an angiotensin-converting-enzyme inhibitor, ramipril, on cardiovascular events in high-risk patients. The Heart Outcomes Prevention Evaluation Study Investigators (2000) N Engl J Med, 342, pp. 145-153; Svensson, P., de Faire, U., Sleight, P., Comparative effects of ramipril on ambulatory and office blood pressures: A HOPE sub-study (2001) Hypertension, 38, pp. E28-E32; White, W.B., Anders, R.J., McIntyre, J.M., Balck, H.R., Sica, D.M., the verapamil study group (1995) Am J Cardiol, 76, p. 375; White, W.B., Black, H.R., Fakouhi, D.T., the COER-Verapamil study group (1997) Am J Cardiol, 80, p. 469; Michael, L., Prisant, M., Weber, M.D., Henry, R.B., Chronotherapeutic oral drug absorption system verapamil is effective in reducing morning blood pressure in African Americans: A post hoc analysis of the chrono trial (2005) J Nat Med Assoc, 97, pp. 377-383; Chasen, C., Muller, J.E., Cardiovascular triggers and morning events (1998) Blood Press Monit, 3, pp. 35-42; Dethlefsen, U., Repges, R., Ein neues Therapieprinzip bei n{\"a}chtlichem Asthma (1985) Med Klin, 80, pp. 44-47; Smolensky, M.H., Scott, P.H., Harrist, R.B., Administration-time-dependency of the pharmacokinetic behavior and therapeutic effect of a once-a-day theophylline in asthmatic children (1987) Chronobiol Int, 4, pp. 435-447; Pincus, D.J., Humeston, T.R., Martin, R.J., Further studies on the chronotherapy of asthma with inhaled steroids: The effect of dosage timing on drug efficacy (1997) J Allergy Clin Immunol, 100, pp. 771-774; Beam, W.R., Weiner, D.E., Martin, R.J., Timing of prednisone and alterations of airways inflammation in nocturnal asthma (1992) Am Rev Respir Dis, 146, pp. 1524-1530; Martin, R.J., Banks, S.S., (1998) Am J Respir Crit Care Med, 158, p. 1002; Pincus, D.J., Humeston, T.R., Martin, R.J., (1997) J. Allergy Clin Immunol, 100, p. 771; Celecoxib product information. Physicians desk reference. 54th ed. Montvale NJ. Med Economics 2000. p. 2334-7, 2901-4; Cutolo M, Seriolo B, Craviotto C, Pizzorini C. Sulli A. Ann Rheum Dis 2003;62:593; Bellamy, N., Sothern, R.V., Campbell, J., Buchanan, W.W., (2002) Ann Rheum Dis, 61, p. 1075; Zoli, A., Lizzio, M.M., Ferlisi, E.M., Massafra, V., Mirone, L., Barini, A., (2002) Clin Rheumatol, 21, p. 289; Smolensky, M.H., D'Alonzo, G.E., Medical chronobiology: Concepts and applications (1993) Am Rev Respir Dis, 147, pp. S2-19; Khasawneh, S.M., Affarah, H.B., Morning versus evening dose: A comparison of three H2-receptor blockers in duodenal ulcer healing (1992) Am J Gastroenterol, 87, pp. 1180-1182; Evans, R.M., Marain, C., Taking your medication: A question of timing (1996) Am Med Assoc, pp. 3-8; Jones, P.J., Schoeller, D.A., Evidence for diurnal periodicity in human cholesterol synthesis (1990) J Lipid Res, 31, pp. 667-673; Jones, P.J., Schoeller, D.A., J Lipid Res, 190 (31), p. 667; Pappu, A.S., Illingworth, D.R., (2002) Atherosclerosis, 165, p. 137; Knopp, R.H., Drug treatment of lipid disorders (1999) N Engl J Med, 341, pp. 498-511; Rivard, G.E., Infante-Rivard, C., Dresse, M.F., Circadian time-dependent response of childhood lymphoblastic leukemia to chemotherapy: A long-term follow-up study of survival (1993) Chronobiol Int, 10, pp. 201-204; Schmiegelow, K., Glomstein, A., Kristinsson, J., For the Nordic Society for Pediatric Hematology and Oncology (NOPHO). Impact of morning versus evening schedule for oral methotrexate and 6-mercaptopurine on relapse risk for children with acute lymphoblastic leukemia (1997) J Pediatr Hematol Oncol, 19, pp. 102-109; Koren, G., Langevin, A.M., Olivieri, N., Diurnal variation in the pharmacokinetics and myelotoxicity of mercaptopurine in children with acute lymphocytic leukemia (1990) Am J Dis Child, 144, pp. 1135-1137; Lamberg, L., Chronotherapeutics: Implications for drug therapy (1991) Am Pharma, NS31, pp. 796-799; Ura, J., Shirachi, D., Ferrill, M., The Chronotherapeutic approach to pharmaceutical treatment (1992) California Pharmacist, 23, pp. 46-53; L{\'e}vi, F., Zidani, R., Misset, J.L., For the International Organization for Cancer Chronotherapy. Randomized multicentre trial of chronotherapy with oxaliplatin, fluorouracil and folinic acid in metastatic colorectal cancer (1997) Lancet, 350, pp. 681-686; Vincenzi, B., Bjarnason, G., Focan, C., Di Paola, E.D., Levi, F., (2003) Pathol Biol Paris, 51, p. 197; Fu, L., Lee, C.C., (2003) Nat Rev Cancer, 3, p. 350; Smolensky, M.H., Reinberg, A., Labrecque, G., Twenty-four hour pattern in symptom intensity of viral and allergic rhinitis: Treatment implications (1995) J Allergy Clin Immunol, 95, pp. 1084-1096; Reinberg, A., Gervais, P., Ugolini, C., (1986) A multicentric chronotherapeutic study of mequitazine in allergic rhinitis, 3, pp. 441-444. , editors, Biological rhythms and medications. Ann Rev Chronopharmacol",
year = "2006",
language = "English",
volume = "38",
pages = "15--18",
journal = "Pharma Times",
issn = "0031-6849",
publisher = "Indian Pharmaceutical Association",
number = "10",

}

Chronotherapeutics and disease management: Treatment in synchrony with body's rhythms - An emerging science. / Aithal, K.B.; Harish, N.M.; Rathnanand, M.; Shirwaikar, A.

In: Pharma Times, Vol. 38, No. 10, 2006, p. 15-18.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Chronotherapeutics and disease management: Treatment in synchrony with body's rhythms - An emerging science

AU - Aithal, K.B.

AU - Harish, N.M.

AU - Rathnanand, M.

AU - Shirwaikar, A.

N1 - Cited By :1 Export Date: 10 November 2017 Correspondence Address: Shirwaikar, A.; Dept. of Pharmaceutics, Manipal College of Pharmaceutical Sciences, Manipal, India; email: arunshirwaikar@yahoo.co.in References: Jha, N., Bapat, S., (2004) Chronobiology and chronotherapeutics, 2, pp. 384-388. , Kathmandu Univ Med J; Levi, F., From circadian rhythms to cancer chronotherapeutics (2002) Chronobiol Int, 19, pp. 1-19; Micheal, H., The brain, circadian rhythms and clock genes (1998) Br Med J, 317, pp. 1704-1708; Isadora, S., A time to heal: Chronotherapy tunes in to body's rhythms (1997) FDA Consumer, 31, pp. 16-20; Sarasija, S., Stutie, P., Chronotherapeutics: Emerging role of biorhythms in optimizing drug therapy (2005) Indian J Pharm Sci, 67, pp. 135-140; Lemmer, B., Chronopharmacology: Time, a key in drug treatment (1994) Ann Biol Clin, 52, pp. 1-7; Reinberg, A.E., Concepts of circadian chronopharmacology (1991) Ann N Y Acad Sci, 618, pp. 102-115; Willich, S.N., Levy, D., Rocco, M.B., Circadian variation in the incidence of sudden cardiac death in the Framingham Heart Study population (1987) Am J Cardiol, 60, pp. 801-806; Pickering, T.G., James, G.D., Determinants and consequences of the diurnal rhythm of blood pressure (1993) Am J Hypertens, 6, pp. 166S-169S; White, W.B., Circadian variation in blood pressure (1997) Blood Press Monit, 2, pp. 46-51; Millar-Craig, M.W., Bishop, C.N., Raftery, E.B., Circadian variation of blood pressure (1978) Lancet, 1, pp. 795-797; Anwar, Y.A., White, W.B., Chronotherapeutics for cardiovascular disease (1998) Drugs, 55, pp. 631-643; Yusuf, S., Sleight, P., Pogue, J., Effects of an angiotensin-converting-enzyme inhibitor, ramipril, on cardiovascular events in high-risk patients. The Heart Outcomes Prevention Evaluation Study Investigators (2000) N Engl J Med, 342, pp. 145-153; Svensson, P., de Faire, U., Sleight, P., Comparative effects of ramipril on ambulatory and office blood pressures: A HOPE sub-study (2001) Hypertension, 38, pp. E28-E32; White, W.B., Anders, R.J., McIntyre, J.M., Balck, H.R., Sica, D.M., the verapamil study group (1995) Am J Cardiol, 76, p. 375; White, W.B., Black, H.R., Fakouhi, D.T., the COER-Verapamil study group (1997) Am J Cardiol, 80, p. 469; Michael, L., Prisant, M., Weber, M.D., Henry, R.B., Chronotherapeutic oral drug absorption system verapamil is effective in reducing morning blood pressure in African Americans: A post hoc analysis of the chrono trial (2005) J Nat Med Assoc, 97, pp. 377-383; Chasen, C., Muller, J.E., Cardiovascular triggers and morning events (1998) Blood Press Monit, 3, pp. 35-42; Dethlefsen, U., Repges, R., Ein neues Therapieprinzip bei nächtlichem Asthma (1985) Med Klin, 80, pp. 44-47; Smolensky, M.H., Scott, P.H., Harrist, R.B., Administration-time-dependency of the pharmacokinetic behavior and therapeutic effect of a once-a-day theophylline in asthmatic children (1987) Chronobiol Int, 4, pp. 435-447; Pincus, D.J., Humeston, T.R., Martin, R.J., Further studies on the chronotherapy of asthma with inhaled steroids: The effect of dosage timing on drug efficacy (1997) J Allergy Clin Immunol, 100, pp. 771-774; Beam, W.R., Weiner, D.E., Martin, R.J., Timing of prednisone and alterations of airways inflammation in nocturnal asthma (1992) Am Rev Respir Dis, 146, pp. 1524-1530; Martin, R.J., Banks, S.S., (1998) Am J Respir Crit Care Med, 158, p. 1002; Pincus, D.J., Humeston, T.R., Martin, R.J., (1997) J. Allergy Clin Immunol, 100, p. 771; Celecoxib product information. Physicians desk reference. 54th ed. Montvale NJ. Med Economics 2000. p. 2334-7, 2901-4; Cutolo M, Seriolo B, Craviotto C, Pizzorini C. Sulli A. Ann Rheum Dis 2003;62:593; Bellamy, N., Sothern, R.V., Campbell, J., Buchanan, W.W., (2002) Ann Rheum Dis, 61, p. 1075; Zoli, A., Lizzio, M.M., Ferlisi, E.M., Massafra, V., Mirone, L., Barini, A., (2002) Clin Rheumatol, 21, p. 289; Smolensky, M.H., D'Alonzo, G.E., Medical chronobiology: Concepts and applications (1993) Am Rev Respir Dis, 147, pp. S2-19; Khasawneh, S.M., Affarah, H.B., Morning versus evening dose: A comparison of three H2-receptor blockers in duodenal ulcer healing (1992) Am J Gastroenterol, 87, pp. 1180-1182; Evans, R.M., Marain, C., Taking your medication: A question of timing (1996) Am Med Assoc, pp. 3-8; Jones, P.J., Schoeller, D.A., Evidence for diurnal periodicity in human cholesterol synthesis (1990) J Lipid Res, 31, pp. 667-673; Jones, P.J., Schoeller, D.A., J Lipid Res, 190 (31), p. 667; Pappu, A.S., Illingworth, D.R., (2002) Atherosclerosis, 165, p. 137; Knopp, R.H., Drug treatment of lipid disorders (1999) N Engl J Med, 341, pp. 498-511; Rivard, G.E., Infante-Rivard, C., Dresse, M.F., Circadian time-dependent response of childhood lymphoblastic leukemia to chemotherapy: A long-term follow-up study of survival (1993) Chronobiol Int, 10, pp. 201-204; Schmiegelow, K., Glomstein, A., Kristinsson, J., For the Nordic Society for Pediatric Hematology and Oncology (NOPHO). Impact of morning versus evening schedule for oral methotrexate and 6-mercaptopurine on relapse risk for children with acute lymphoblastic leukemia (1997) J Pediatr Hematol Oncol, 19, pp. 102-109; Koren, G., Langevin, A.M., Olivieri, N., Diurnal variation in the pharmacokinetics and myelotoxicity of mercaptopurine in children with acute lymphocytic leukemia (1990) Am J Dis Child, 144, pp. 1135-1137; Lamberg, L., Chronotherapeutics: Implications for drug therapy (1991) Am Pharma, NS31, pp. 796-799; Ura, J., Shirachi, D., Ferrill, M., The Chronotherapeutic approach to pharmaceutical treatment (1992) California Pharmacist, 23, pp. 46-53; Lévi, F., Zidani, R., Misset, J.L., For the International Organization for Cancer Chronotherapy. Randomized multicentre trial of chronotherapy with oxaliplatin, fluorouracil and folinic acid in metastatic colorectal cancer (1997) Lancet, 350, pp. 681-686; Vincenzi, B., Bjarnason, G., Focan, C., Di Paola, E.D., Levi, F., (2003) Pathol Biol Paris, 51, p. 197; Fu, L., Lee, C.C., (2003) Nat Rev Cancer, 3, p. 350; Smolensky, M.H., Reinberg, A., Labrecque, G., Twenty-four hour pattern in symptom intensity of viral and allergic rhinitis: Treatment implications (1995) J Allergy Clin Immunol, 95, pp. 1084-1096; Reinberg, A., Gervais, P., Ugolini, C., (1986) A multicentric chronotherapeutic study of mequitazine in allergic rhinitis, 3, pp. 441-444. , editors, Biological rhythms and medications. Ann Rev Chronopharmacol

PY - 2006

Y1 - 2006

M3 - Article

VL - 38

SP - 15

EP - 18

JO - Pharma Times

JF - Pharma Times

SN - 0031-6849

IS - 10

ER -