We report a case of a patient aged 65 years' who presented with histopathological proven metastatic squamous cell cancer of the anal canal. After the necessary workup she was planned for Cisplatin and Fluoropyrimidine based palliative chemotherapy. On day 4 following chemotherapy the patient developed an episode of Generalized Tonic Clonic Seizures, which on further evaluation was attributed to hyponatremia as a result of SIADH secondary to Cisplatin. She required ICU care but made a complete recovery. Patient subsequently refused IV chemotherapy, thereafter she was managed on single agent oral capecitabine and is on follow up to date.
|Number of pages||4|
|Journal||Research Journal of Pharmaceutical, Biological and Chemical Sciences|
|Publication status||Published - 01-01-2015|
All Science Journal Classification (ASJC) codes
- Biochemistry, Genetics and Molecular Biology(all)
- Pharmacology, Toxicology and Pharmaceutics(all)